Protein Info for SO0144 in Shewanella oneidensis MR-1

Name: ptrB
Annotation: protease II (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 PF02897: Peptidase_S9_N" amino acids 16 to 411 (396 residues), 328.9 bits, see alignment E=4.5e-102 PF00326: Peptidase_S9" amino acids 477 to 698 (222 residues), 229.4 bits, see alignment E=3.6e-72

Best Hits

KEGG orthology group: K01354, oligopeptidase B [EC: 3.4.21.83] (inferred from 100% identity to son:SO_0144)

Predicted SEED Role

"Protease II (EC 3.4.21.83)" (EC 3.4.21.83)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8EKF0 at UniProt or InterPro

Protein Sequence (700 amino acids)

>SO0144 protease II (NCBI ptt file) (Shewanella oneidensis MR-1)
MLLPGCSTQKGQVSAPVAEKIPHVMTLHGVTRTDDYYWMRDDKRQDPKVLAHLKAENRYT
QAYFKPLKSLQDGLFNELTGRLVADESSVPYQWHQHSYYRRYQEGSEYPLIARKGSKGVE
QLMLDVNERAKGHEFYGLGGVSVSPDETMLAFGEDVLSRRVYNIYFKDIESGAMITDVLE
NTEGRIVWGNDNRHVFYIAKDLQTLLGNRVYRHELGTPQSRDVLVYEEQDDAYYISLGKS
LDESQIVLFHESTTTSEVSVLDANDPLSLFKPVLAREEGHEYSVSKLGDSYYVLTNWQAT
NFRLMKVAIKDAADKSKWQEVVAHNPNARLEDELVLKDYLIIQTRENGLTRIKVMPFNGQ
KPFELSFDEPAYVLGLDVNAQQDSDKLRVFYSSLTTPETIYEYHLSNPDRRDLLKQEQVL
GGFDAGAYRAERVFVTARDGAKVPVSLVYRKDKFKKDGTNPLYQYGYGSYGYTVEPDFSS
SVISLLDRGFVYAIAHVRGGEMLGRPWYDAGKLLNKKNSFYDFIDVTTALTEQGYGDKNK
VVAAGGSAGGLLMGAIANMAPEKYFAIAAHVPFVDVVTTMLDESIPLTTNEYDEWGNPND
KTYFDYMLSYSPYDNVADHEYPHLLVTTGLHDSQVQYFEPAKWVAKLREVQNKWYKLDDK
VLLFHVDMDAGHGGKSGRYRQYQDTAQEYAFFLSLLGMTK