Protein Info for Rru_A3772 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function UPF0054 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 PF02130: YbeY" amino acids 70 to 178 (109 residues), 112.4 bits, see alignment E=7.2e-37 TIGR00043: rRNA maturation RNase YbeY" amino acids 72 to 179 (108 residues), 110.3 bits, see alignment E=2.7e-36

Best Hits

Swiss-Prot: 100% identical to YBEY_RHORT: Endoribonuclease YbeY (ybeY) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K07042, probable rRNA maturation factor (inferred from 100% identity to rru:Rru_A3772)

Predicted SEED Role

"Metal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RMS9 at UniProt or InterPro

Protein Sequence (200 amino acids)

>Rru_A3772 Protein of unknown function UPF0054 (NCBI) (Rhodospirillum rubrum S1H)
MPADPALPDPVPPGPTAPVPTDYPVRLAVDGAEGPWEALVPGVAALVEQAVLAAVAAGDP
SGYGLTPGTPLEISLLLTDDAAVQALNRDYRGQDKPTNVLSFAALDAEEPLPEDGEPVLL
GDVALARETVVREAADLGIAPADHVFHLVVHGVLHLLGYDHEEEEEALDMEGLETAILGA
RGIADPYADARGPEQEGSDR