Protein Info for Rru_A3763 in Rhodospirillum rubrum S1H

Annotation: Peptidase M22, glycoprotease (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 transmembrane" amino acids 15 to 32 (18 residues), see Phobius details TIGR03725: tRNA threonylcarbamoyl adenosine modification protein YeaZ" amino acids 15 to 217 (203 residues), 148.3 bits, see alignment E=1.5e-47 PF00814: TsaD" amino acids 44 to 136 (93 residues), 79.7 bits, see alignment E=1.6e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3763)

Predicted SEED Role

"TsaB protein, required for threonylcarbamoyladenosine (t(6)A) formation in tRNA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RMT8 at UniProt or InterPro

Protein Sequence (232 amino acids)

>Rru_A3763 Peptidase M22, glycoprotease (NCBI) (Rhodospirillum rubrum S1H)
MSLSAAKPDGGPPTVLAIDTALAACSVAVVAADRPAVSRHQPMARGQAEVLMPMIAEVMA
AAGLGYGDLDLIAVTSGPGSFTGLRVGLATARGLALACGRPAAGIAVPMVLADAALAQAP
DRPALVLLDNRRGEVHGQSFHGRDDRGLPLAAGPLLTLDLDAARALLGEGPTTLAGDGAA
LLGCAVAPGLIFADPLRLADLAARGLGERPPRPLYLRPPDAIAPRDGGRLRP