Protein Info for Rru_A3619 in Rhodospirillum rubrum S1H

Annotation: transcription termination factor Rho (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 TIGR00767: transcription termination factor Rho" amino acids 2 to 417 (416 residues), 717.7 bits, see alignment E=2.1e-220 PF07498: Rho_N" amino acids 5 to 46 (42 residues), 64 bits, see alignment 1.5e-21 PF07497: Rho_RNA_bind" amino acids 52 to 125 (74 residues), 117.8 bits, see alignment E=2.2e-38 PF00006: ATP-synt_ab" amino acids 159 to 363 (205 residues), 100.5 bits, see alignment E=1.6e-32

Best Hits

Swiss-Prot: 78% identical to RHO_RICBR: Transcription termination factor Rho (rho) from Rickettsia bellii (strain RML369-C)

KEGG orthology group: K03628, transcription termination factor Rho (inferred from 100% identity to rru:Rru_A3619)

Predicted SEED Role

"Transcription termination factor Rho" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RN82 at UniProt or InterPro

Protein Sequence (418 amino acids)

>Rru_A3619 transcription termination factor Rho (NCBI) (Rhodospirillum rubrum S1H)
MHLQELKSKSPADLLAFAEELEIENASNLRKQDMMFAILKQLAENDTAIFGEGVLEILQD
GFGFLRAPESNYLPGPDDIYVSPSQVRRFGLRTGDTVEGQIRAPKDGERYFALLKVNKIN
FEAPESVRHRINFDNLTPLYPDERLKLEIDDPTRKEFTTRIIDLITPLGKGQRALIVAPP
RTGKTVMLQNVAHAISANNPEVYLIVLLIDERPEEVTDMARSVNGEVVSSTFDEPASRHV
QVAEMVIEKAKRLVEHKRDVVILLDSITRLARAYNTVVPSSGKVLTGGVDANALQRPKRF
FGAARNIEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNSEIILDRKLADRRVFPSIDI
ARSGTRKEELLVRKDVLSKMWVLRRILSPMGVQDAMEFLLGKMKETKNNDDFFDAMNS