Protein Info for Rru_A3600 in Rhodospirillum rubrum S1H

Annotation: Heat shock protein HslU (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 TIGR00390: ATP-dependent protease HslVU, ATPase subunit" amino acids 5 to 435 (431 residues), 604.2 bits, see alignment E=8e-186 PF07728: AAA_5" amino acids 52 to 88 (37 residues), 25.7 bits, see alignment 3.2e-09 PF00004: AAA" amino acids 53 to 135 (83 residues), 31.1 bits, see alignment E=9.1e-11 amino acids 224 to 324 (101 residues), 31.6 bits, see alignment E=6.1e-11 PF07724: AAA_2" amino acids 193 to 321 (129 residues), 90.7 bits, see alignment E=3.4e-29

Best Hits

Swiss-Prot: 100% identical to HSLU_RHORT: ATP-dependent protease ATPase subunit HslU (hslU) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K03667, ATP-dependent HslUV protease ATP-binding subunit HslU (inferred from 100% identity to rru:Rru_A3600)

Predicted SEED Role

"ATP-dependent hsl protease ATP-binding subunit HslU" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNA1 at UniProt or InterPro

Protein Sequence (435 amino acids)

>Rru_A3600 Heat shock protein HslU (NCBI) (Rhodospirillum rubrum S1H)
MNAFTPREIVSELDRHIVGQKDAKRAVAIALRNRWRRQQLSEALRDEVLPKNILMIGPTG
VGKTEIARRLAKLAQAPFLKVEATKFTEVGYVGRDVESIIRDLVETALTQERDRLRKQVN
AKAEANAEERVLDALVGDRASPETRQKFRKMLREGQINDKEIEVQVQDSGGALPTMDIPG
MPGAQMGMLNLNDIFGKAFGNRTKARKMTVEDSHAVLVREEADKLLDEEQVVKAAIAAVE
NNGIVFLDEIDKIATASERRGGDVSREGVQRDLLPLIEGTTVSTKYGPVKTDHVLFIASG
AFHTAKPADLLPELQGRLPIRVELSALNAGDFKRILLEPEASLITQYKALLATEGVTLEF
PDDTVEAIAEIATEINGSVENIGARRLHTVLERLLEEISFTATDRSGETIVVTRDMVKER
VGALAAKADLSRFIL