Protein Info for Rru_A3551 in Rhodospirillum rubrum S1H

Annotation: Aldo/keto reductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 PF00248: Aldo_ket_red" amino acids 22 to 289 (268 residues), 246.8 bits, see alignment E=1.3e-77

Best Hits

Swiss-Prot: 54% identical to YH5B_SCHPO: Uncharacterized oxidoreductase C215.11c (SPBC215.11c) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3551)

Predicted SEED Role

"L-fuco-beta-pyranose dehydrogenase (EC 1.1.1.122)" (EC 1.1.1.122)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.122

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNF0 at UniProt or InterPro

Protein Sequence (300 amino acids)

>Rru_A3551 Aldo/keto reductase (NCBI) (Rhodospirillum rubrum S1H)
MIFPNASQSGSFLIGGDLPVNRLGFGAMRVTGPGVWGAGPQPVEALKTLKMLPEVGVTLI
DTADSYGPGISEAMIAEALYPYEGANADLVIATKGGLVRPAPDVWIPLGRPEYLRQQAQV
SRRTLKVEKIGLWQLHRIDPKVPRDEQFDAIKSLIDDGIIAHAGLSEVTIADIEEASDYF
PVATVQNRYNMLDRASEPVLEYCEAKGIGFIPWSPLGAGGLFDAGSELAVLAKRWSITPG
QIALAWLLKRSPVILPIPGTSKRAHLQENIAAAAIVLTDDDFSAFDQLARDYARKIAQTA