Protein Info for Rru_A3550 in Rhodospirillum rubrum S1H

Annotation: Cobyric acid synthase CobQ (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 PF13500: AAA_26" amino acids 21 to 250 (230 residues), 35.2 bits, see alignment E=1.8e-12 TIGR00313: cobyric acid synthase CobQ" amino acids 23 to 506 (484 residues), 378.7 bits, see alignment E=2.2e-117 PF01656: CbiA" amino acids 24 to 261 (238 residues), 54.9 bits, see alignment E=1.3e-18 PF07685: GATase_3" amino acids 278 to 464 (187 residues), 177.9 bits, see alignment E=2.9e-56

Best Hits

Swiss-Prot: 56% identical to COBQ_AZOC5: Cobyric acid synthase (cobQ) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K02232, adenosylcobyric acid synthase [EC: 6.3.5.10] (inferred from 100% identity to rru:Rru_A3550)

Predicted SEED Role

"Cobyric acid synthase (EC 6.3.5.10)" (EC 6.3.5.10)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.3.5.10

Use Curated BLAST to search for 6.3.5.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNF1 at UniProt or InterPro

Protein Sequence (513 amino acids)

>Rru_A3550 Cobyric acid synthase CobQ (NCBI) (Rhodospirillum rubrum S1H)
MTDDPTIAFQRLKNPHPLRARGLMLQGTASDVGKSLLVAGLCRAYTRRGLVVRPFKAQNM
SNNAAVTLDGEHPGQRGEIGRAQALQARACKAPCSVHMNPVLLKPESDIDCQVVLRGQVL
GRWSASAYQRLKPKLMPAVLDSLERLGAEADLLVVEGAGCGAERYLRAQDITNMALAEAA
DLAVCIIADESRGGVMAALLGMHGLLDPSERQRVIGYIVNKFRGDPRVFDPAAEEITARS
GWANLGLVGWFDAAGRLPAEDSLALARPRAAGAGALTLAVPRLSRIANFDDLDPLAAEPG
VRVIWVAPGQPIPRDADVIVLPGSKATRADLAMLRAEGWDIDILAHVRQGGRVVGLCAGF
QMLGQVVRDPQGIEGPAGESAGLGLLDIETVIGGEKRLVDLAVTERRSGCALTGYEMHMG
TTRGPGLARPWLVFDDHGAPRPQGACSADGRVMGAYVHGIFAADGFRAHWLGQVGAPPSS
LLFEDRIEGALDALADHCEAALDLDRLWELARR