Protein Info for Rru_A3497 in Rhodospirillum rubrum S1H

Annotation: Disulphide bond formation protein DsbB (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 177 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details transmembrane" amino acids 50 to 68 (19 residues), see Phobius details amino acids 76 to 96 (21 residues), see Phobius details amino acids 147 to 169 (23 residues), see Phobius details PF02600: DsbB" amino acids 14 to 166 (153 residues), 106.1 bits, see alignment E=1.1e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3497)

Predicted SEED Role

"Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNK4 at UniProt or InterPro

Protein Sequence (177 amino acids)

>Rru_A3497 Disulphide bond formation protein DsbB (NCBI) (Rhodospirillum rubrum S1H)
MPPMPAACPFRGLRLLALALLLVSGGALMAALYAEFALGLEPCVLCLYERGPWVLAALLC
AIAFQPGLDASWRRRLLGLCALAFFGNALLAGFHIGVEQHWWAGTDACGPTAAGPGVGSL
GDLRAAMSAPAPATARCDTPSWTFHGLTLAGLNLILSLILGGVTGWRVLRRDDSHPI