Protein Info for Rru_A3492 in Rhodospirillum rubrum S1H
Annotation: Periplasmic Sensor Hybrid Histidine Kinase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3492)Predicted SEED Role
"Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 2.3.1.39)
MetaCyc Pathways
- superpathway of fatty acids biosynthesis (E. coli) (48/53 steps found)
- superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
- superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
- superpathway of fatty acid biosynthesis initiation (5/5 steps found)
- fatty acid biosynthesis initiation (type II) (3/3 steps found)
- fatty acid biosynthesis initiation (mitochondria) (3/4 steps found)
- fatty acid biosynthesis initiation (plant mitochondria) (1/4 steps found)
- mycobactin biosynthesis (1/11 steps found)
- pederin biosynthesis (2/14 steps found)
- bryostatin biosynthesis (2/19 steps found)
- mupirocin biosynthesis (1/26 steps found)
- corallopyronin A biosynthesis (2/30 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.3.1.39
Use Curated BLAST to search for 2.3.1.39
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RNK9 at UniProt or InterPro
Protein Sequence (1041 amino acids)
>Rru_A3492 Periplasmic Sensor Hybrid Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H) MNMDRSNDLAGTLPAPPSVPGPAEDGQSMPIFRWIWRSYLRSALIPLVFIELVFLAIYLL SHQISTSRTLESFGSAVENEFYGAAEREAALLSERLAALGTTASVFAHQAARVLSTPCQP APRERARLALGANGVLYSTGAPEGSAALFYSGIIPVGPAQIDKAVCSAALDPLMRDISAV EPLVDQIYVNTWDSMNRIYPPIDVLSQYAPHMDIPSFNFFYEADQEHNPERKVVWTDVYL DPAGRGWIASAIAPAYRGTILEGVVGLDVTVGTFIDRVLAAELPFDAYGLLLDRNGGILG APKVAGEDWGAKPLTEATYGGAITKDTFVDPAFNLFARAEPADLLAALQSQSNGVRPVTL AGKQKVVAWAKVASTGWTYLMVADRDTVFGDILRLDRLFTVIGYLMAGGLLVFYLGFLAF LYIRVREMSVRLSGPLSALNAMIRRIASGSYFQTAPAFDVRELDETGREVAAMGDRLGRA NEELIANREELVRARDAAQAAARAKAEFLATMSHEIRTPMNAVIGMTGLLLDGPLEPRQI DYARTIQRSGEHLLGLINDILDFSRIDTGRLVLVDRDFSLSHEVQAVVSLCGVAASAKRL SVRIDLDRALAPGYRGDSQRLRQILVNLVGNAVKFTDKGMVTVQGDVLKIENDIHWLRLR VVDTGCGIPRERFNDLFAAFQQLDGSATRTHGGTGLGLAISRKLARLMGGDITVSSTPGE GSVFSVVVPMVPLSRTPAPDGTLGDGDAERGEEPPAADVPTEAAASRALVVLVAEDILEN QILVQAVLEKQGHRVILAANGREALAKLRGADPVDVVLMDIQMPVMDGLDACRAIRGLPP EVHFSDGRPIAGVPIIAFTADALPGDRERFLSAGMNEHLAKPLNARRLRALLGDIAAGRP LTPRSSAAPSPRKSLEAPRRLLDPEALAQLRTSLGEDYPIYLRAAEEALRHRARALPEAL ARGAFEEASQLLHGLRGTLAAFGMEAEATLCQRLRGDLAGGAGIAIRVEARKLADQALAA ADEVRGHRGLPSIDPRAPTPL