Protein Info for Rru_A3488 in Rhodospirillum rubrum S1H

Annotation: Initiation factor 3 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 173 PF05198: IF3_N" amino acids 13 to 81 (69 residues), 114.7 bits, see alignment E=1.8e-37 TIGR00168: translation initiation factor IF-3" amino acids 13 to 173 (161 residues), 239.7 bits, see alignment E=6.6e-76 PF00707: IF3_C" amino acids 88 to 173 (86 residues), 140.8 bits, see alignment E=1.1e-45

Best Hits

Swiss-Prot: 71% identical to IF3_BRUME: Translation initiation factor IF-3 (infC) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 100% identity to rru:Rru_A3488)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNL3 at UniProt or InterPro

Protein Sequence (173 amino acids)

>Rru_A3488 Initiation factor 3 (NCBI) (Rhodospirillum rubrum S1H)
MQAPPSKDGPRANREIRIPEVRLIDENGDNVGVVSTRDALARAEAAGLDLVEISPNAEPP
VCKILDLGKFKYEAQKKKNEAKKKQKVIEIKEIKLRPNIDEHDYDVKMRAAKRFLEEGDK
VKVTMRFRGREMAHQDLGMNVLKRVSEDVADLAKVEQHPKLEGRQMIMVMAPK