Protein Info for Rru_A3480 in Rhodospirillum rubrum S1H

Annotation: succinyl-diaminopimelate desuccinylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 TIGR01246: succinyl-diaminopimelate desuccinylase" amino acids 18 to 397 (380 residues), 378.9 bits, see alignment E=1.3e-117 PF01546: Peptidase_M20" amino acids 80 to 396 (317 residues), 127.6 bits, see alignment E=6.4e-41 PF07687: M20_dimer" amino acids 198 to 300 (103 residues), 73 bits, see alignment E=1.8e-24

Best Hits

Swiss-Prot: 100% identical to DAPE_RHORT: Succinyl-diaminopimelate desuccinylase (dapE) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K01439, succinyl-diaminopimelate desuccinylase [EC: 3.5.1.18] (inferred from 100% identity to rru:Rru_A3480)

Predicted SEED Role

"N-succinyl-L,L-diaminopimelate desuccinylase (EC 3.5.1.18)" in subsystem Arginine Biosynthesis extended or Lysine Biosynthesis DAP Pathway (EC 3.5.1.18)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.18

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNM1 at UniProt or InterPro

Protein Sequence (404 amino acids)

>Rru_A3480 succinyl-diaminopimelate desuccinylase (NCBI) (Rhodospirillum rubrum S1H)
MSALPLRWTAAELADPLALARALVACPSVTPRDAGALDVLESALIALGFRCVRLPFGAEG
GERVDNLYARRGGAGPCFGFAGHTDVVPAGDGWSRPPFGAEVVDGALVGRGAADMKGGIA
CFVAAVARLISGPDSTGSISRHDPTGSIALLITGDEEGPALHGTRKVLEWMEGAGERMDL
CLVGEPTNPEGLGDMIKIGRRGSLTATVTLLGRAGHVAYPHLADNPLHRLSTLTGLLLAE
TLDDGTAHFQPSSLQLTSIDVGNPAANVIPAKATLRFNIRFNDRHSGESLSAWIRARCLA
ACDGDESGFSLVLEHSGDAFLTPPGPLSDLIATACQAVTGRRPELSTSGGTSDARFIRSH
CPVAEFGLVGRTMHKPDERVAVADLEALSEIYRRVLVGFFEAPC