Protein Info for Rru_A3421 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF461 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF04314: PCuAC" amino acids 47 to 153 (107 residues), 138.1 bits, see alignment E=5.2e-45

Best Hits

KEGG orthology group: K09796, hypothetical protein (inferred from 100% identity to rru:Rru_A3421)

Predicted SEED Role

"Copper metallochaperone, bacterial analog of Cox17 protein" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNT0 at UniProt or InterPro

Protein Sequence (191 amino acids)

>Rru_A3421 Protein of unknown function DUF461 (NCBI) (Rhodospirillum rubrum S1H)
MSVRRSLLSACAVLCLGGAFALPLAPAPALANDDGARAEATAGTITVSDAWARATPGAAK
VGGAFLTLTNTGDADRLLSASADVSETVELHTHIMDGTVMRMRQVDAIDLPAKGSVALRP
GSFHVMLIGLKAPLSEGQSFPLTLTFEKAGKATIDVTVKGAGAMGGAAPKPDHGAMPGMT
MPGHGDGAAAK