Protein Info for Rru_A3377 in Rhodospirillum rubrum S1H

Annotation: Alpha/beta hydrolase fold (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 PF12697: Abhydrolase_6" amino acids 33 to 234 (202 residues), 36.2 bits, see alignment E=2.2e-12 PF00561: Abhydrolase_1" amino acids 33 to 151 (119 residues), 46.1 bits, see alignment E=1e-15 PF12146: Hydrolase_4" amino acids 33 to 139 (107 residues), 46.6 bits, see alignment E=5.8e-16 PF00326: Peptidase_S9" amino acids 87 to 239 (153 residues), 30.2 bits, see alignment E=6.5e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3377)

Predicted SEED Role

"2-hydroxymuconic semialdehyde hydrolase (EC 3.1.1.-)" (EC 3.1.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.-

Use Curated BLAST to search for 3.1.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNX4 at UniProt or InterPro

Protein Sequence (256 amino acids)

>Rru_A3377 Alpha/beta hydrolase fold (NCBI) (Rhodospirillum rubrum S1H)
MSTDLAERAPSILTDLDGATIAYHRTPGKSPGVVFIHGFMSNMDGGKALFVENWCRNHGR
AFLRFDQTGHGLSSGAFEEGSIGRWAADTIAVLDALTSGPQVLIGSSMGGWLMLLAALAR
PDRVAGLIGLAAAPDFTEDLIWDQASPEIRETLLREGRVEEAGSGDEGPTVFTKLLIEDG
RRHLLLRAPLAIECPVRLIHGLGDQSVPWETALRLQKALRASDVSVTLVKDGEHRLSRPQ
DLDRLGRTLEALLAQL