Protein Info for Rru_A3363 in Rhodospirillum rubrum S1H

Annotation: PAS/PAC Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 515 PF13188: PAS_8" amino acids 12 to 70 (59 residues), 17.9 bits, see alignment 5.9e-07 amino acids 133 to 191 (59 residues), 20.5 bits, see alignment 9.1e-08 TIGR00229: PAS domain S-box protein" amino acids 16 to 125 (110 residues), 37.5 bits, see alignment E=1.2e-13 amino acids 135 to 254 (120 residues), 44.3 bits, see alignment E=9.3e-16 PF08448: PAS_4" amino acids 20 to 122 (103 residues), 27.6 bits, see alignment E=7.4e-10 amino acids 138 to 249 (112 residues), 47.1 bits, see alignment E=6.5e-16 PF13426: PAS_9" amino acids 22 to 119 (98 residues), 34.7 bits, see alignment E=4.6e-12 amino acids 144 to 245 (102 residues), 28.4 bits, see alignment E=4.2e-10 PF00989: PAS" amino acids 135 to 244 (110 residues), 34.8 bits, see alignment E=3.6e-12 PF02518: HATPase_c" amino acids 378 to 490 (113 residues), 85.3 bits, see alignment E=1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3363)

Predicted SEED Role

"Phytochrome, two-component sensor histidine kinase (EC 2.7.3.-); Cyanobacterial phytochrome B" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RNY8 at UniProt or InterPro

Protein Sequence (515 amino acids)

>Rru_A3363 PAS/PAC Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MSGEPVGLALQRLYDLTRLVSDWIWETDSAGLLTYASDRVFEILGYPARALIGHPFAELA
ASGDPPFFKSDPRPFREQRFEARHSDGSPRVLLISAVPLFDAQSGDRQGWRGAAKDITQS
ERADAEMDRQRRFQQTLLDAIPLPVFLKDREDRYQGCNLAFETASGRSRAEILGQRMEQV
LRSENYDRHRAEEALVLREGRTRVWEAMEHDVSGRHKLISITASPYREPGDPTVRGLIGV
VSDITRRQRAEDALRASVVELTASNRELQHFAEIAAHDLQEPVRAVVSHCQLLERHLGDA
LDGPARDHMIFAITGARRMRDLIQDLLIYARAGRDGQFHEVVDTADLAREVVSALADEIA
ASGATIRIDPLPSVLGRRRDLFDVMVNLFDNALKFRRPDVVPEVTLKAAETLDASGLWCF
TLSDNGIGLDPVHGAQIFALFRRLHGADRYPGTGVGLAICRRIVEQHGGTIFVESAPGVG
TRFHFTLPAAPSEEPDRLVGRGTRSAPRPVIDGGG