Protein Info for Rru_A3339 in Rhodospirillum rubrum S1H

Annotation: 60 kDa inner membrane insertion protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 384 to 411 (28 residues), see Phobius details amino acids 456 to 479 (24 residues), see Phobius details amino acids 517 to 534 (18 residues), see Phobius details amino acids 553 to 575 (23 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 390 (387 residues), 284.6 bits, see alignment E=1.7e-88 PF14849: YidC_periplas" amino acids 103 to 379 (277 residues), 258.9 bits, see alignment E=8.8e-81 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 391 to 589 (199 residues), 237.2 bits, see alignment E=1.5e-74 PF02096: 60KD_IMP" amino acids 392 to 589 (198 residues), 213.9 bits, see alignment E=1.4e-67

Best Hits

Swiss-Prot: 52% identical to YIDC_METS4: Membrane protein insertase YidC (yidC) from Methylobacterium sp. (strain 4-46)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 100% identity to rru:Rru_A3339)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RP12 at UniProt or InterPro

Protein Sequence (595 amino acids)

>Rru_A3339 60 kDa inner membrane insertion protein (NCBI) (Rhodospirillum rubrum S1H)
MLQQRNLILAIVLSMAVLFGFEYFFGAKQPPMTAQQQDSAQMAAPSNGQMAAPSSVQAPG
QSPVAAPQVPAQPGAAVPTPGGMTPGAASLSREEALAADISPRIGIDTARLHGSIRLRGA
RIDDLSLVDYRETVDPQSPEISLLSPPGAPLPYYAEFGWVAGTPGVKVPDADTLWQADRG
ALGVDAPVTLTWDNGEGLRFIRKIAIDHDFMFSITQAVENTGAGAVTLFPYGLVSRINTP
ALLNYYILHEGPLGVFDGTLKEVKYSALKDDGEVKHTSTGGWMGITDKYWLTALVTDQSM
PVTGRFLYQPRDGRDGYQADFLGAAFTVEPGGRIETSNHLFSGAKEVKLLDRYTDELGIK
NFDLAIDFGWFYFMTKPFFLSIQFLHGILGNMGLAILAFTVVLKLVFFPLANKSYRSMSK
MKLLQPELKKLQERFKDDRARLNQEMMSLYKKEQVNPLSGCLPIVIQIPVFFALYKVLFV
SIEMRHEPFYGWIRDLAAPDPTTVFNLFGLIPWDPPNMLMLGAWPLIMGVTMWMQQKLNP
TPADPTQAKIMMFLPIMFTFMLAHFAAGLVIYWTWNNLLSITQQWVIMKRMGAKT