Protein Info for Rru_A3332 in Rhodospirillum rubrum S1H

Annotation: Cytochrome c oxidase cbb3-type, subunit I (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 transmembrane" amino acids 25 to 48 (24 residues), see Phobius details amino acids 68 to 89 (22 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 137 to 159 (23 residues), see Phobius details amino acids 168 to 190 (23 residues), see Phobius details amino acids 219 to 241 (23 residues), see Phobius details amino acids 251 to 269 (19 residues), see Phobius details amino acids 288 to 309 (22 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 397 to 420 (24 residues), see Phobius details amino acids 448 to 470 (23 residues), see Phobius details TIGR00780: cytochrome c oxidase, cbb3-type, subunit I" amino acids 20 to 482 (463 residues), 748.2 bits, see alignment E=1.9e-229 PF00115: COX1" amino acids 21 to 458 (438 residues), 411.7 bits, see alignment E=1.9e-127

Best Hits

Swiss-Prot: 71% identical to FIXN_RHIME: Cytochrome c oxidase subunit 1 homolog, bacteroid (fixN) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K00404, cb-type cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 100% identity to rru:Rru_A3332)

MetaCyc: 68% identical to cytochrome cbb3 oxidase subunit I (Rhodobacter capsulatus)
CYTOCHROME-C-OXIDASE-RXN [EC: 7.1.1.9]

Predicted SEED Role

"Cytochrome c oxidase subunit CcoN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1 or 7.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RP19 at UniProt or InterPro

Protein Sequence (496 amino acids)

>Rru_A3332 Cytochrome c oxidase cbb3-type, subunit I (NCBI) (Rhodospirillum rubrum S1H)
MTQATIARGARADTEPYVEGVIKKFVIAAVLWGVVGFIAGDVIAWQLAFPSLNMDLEWTS
FGRLRPLHTSAVVFAFGGNVLLGTSLYVVQRTSRASLYGGAALGNIIFWGYQLFIVMAAL
GYVLGVTQGKEYAEPEWFVDLFLTVVWVLYLAAFLGTLLKRREPHIYVANWFFLAMIITI
ALLHLGNNMAIPVALMGGDSWVKSYGFYSGVQDAMTQWWYGHNAVGFFLTAGFLGIMYYF
VPKQAQRPVYSYRLSIVHFWALIFLYIWAGPHHLHYTALPDWAQTVGMVFSVMLWMPSWG
GMINGLMTLSGAWDKLRTDPVLRFLVVSVGFYGMSTFEGPMMSIKAVNSLSHYTDWTIGH
VHSGALGWVAFVSFGALYYLVPALWKRRSLYSLKLVSLHFWIATLGIVLYITSMWVSGIM
QGLMWRAYDELGFLQYSFIESVAAMHPYYIIRATGGVLFVIGSVVMVYNMYRTIKGDIRE
DAPQAAYLGSAAGVRR