Protein Info for Rru_A3330 in Rhodospirillum rubrum S1H

Annotation: Cytochrome c oxidase cbb3-type, subunit III (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 transmembrane" amino acids 33 to 55 (23 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 12 to 291 (280 residues), 301.1 bits, see alignment E=4.1e-94 PF14715: FixP_N" amino acids 13 to 58 (46 residues), 83.2 bits, see alignment 1.6e-27 PF13442: Cytochrome_CBB3" amino acids 112 to 194 (83 residues), 50.4 bits, see alignment E=4.5e-17 amino acids 206 to 284 (79 residues), 34.1 bits, see alignment E=5.5e-12 PF00034: Cytochrom_C" amino acids 114 to 195 (82 residues), 46 bits, see alignment E=2.2e-15 amino acids 207 to 287 (81 residues), 35.1 bits, see alignment E=5.5e-12

Best Hits

Swiss-Prot: 46% identical to FIXP_SINMW: Cbb3-type cytochrome c oxidase subunit FixP (fixP) from Sinorhizobium medicae (strain WSM419)

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 100% identity to rru:Rru_A3330)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RP21 at UniProt or InterPro

Protein Sequence (291 amino acids)

>Rru_A3330 Cytochrome c oxidase cbb3-type, subunit III (NCBI) (Rhodospirillum rubrum S1H)
MAGIPEKDAISGQSTTGHEWDGITELNTPLPAWWVWVFYATIVWALAYVVVYPAIPLGAS
ATPGLFGWHSRTELQKDMNQAYQAFHADKVARIESMDVDAIIADDPLRQYATRAGEVIFK
ENCAPCHQSGGAGNYGYPTLADDEWLWGGTADAIYTTVRHGIRDTNTFDDTRFNEMPSFA
ELPEEDLNALADYVVAASAGSLPAGHGQQLFEENCAVCHASESSGPVPDGNQAMGAPALN
NQIWLYKGDKESILAQLRAPKQGMMPGWANRLKDSDIKSATVYVHSLGGGQ