Protein Info for Rru_A3288 in Rhodospirillum rubrum S1H

Annotation: Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 transmembrane" amino acids 70 to 89 (20 residues), see Phobius details amino acids 338 to 363 (26 residues), see Phobius details PF07536: HWE_HK" amino acids 425 to 478 (54 residues), 26.8 bits, see alignment 1.5e-09 PF07568: HisKA_2" amino acids 425 to 495 (71 residues), 77.1 bits, see alignment E=1.8e-25 PF13581: HATPase_c_2" amino acids 518 to 647 (130 residues), 32.7 bits, see alignment E=1.4e-11 PF02518: HATPase_c" amino acids 525 to 650 (126 residues), 42.9 bits, see alignment E=1.2e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3288)

Predicted SEED Role

"COG3920: Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RP62 at UniProt or InterPro

Protein Sequence (662 amino acids)

>Rru_A3288 Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MTRTAESFPAAHGASGEATESASVSPPRAPSAPSGATPSGPSPPDLPARGRKRQVLARLI
GRGVPLRRQVLALLILALLPGALYAGLMAHNSYTTDRERAREHLRQQAIAAAAQESAAIT
GAEQVGKALALLPILTADPEICRESIDRIRRGFPAYQSIFVVDTGGGVICSAIRPGVDMP
ASVAERPWFKALMSQGRPARASEISPVIRDQPAILVAIPIPGPDGLPRGAVGLVPRLEGG
AMPGKRFRADGGEAILVDTEGKPLPGSESLAMLPDAALLSGLQATSDRPAVFDAPGRDGQ
PRSYALVPLPRGSVNLLFARPEASAFDWAQRDVVTRLVGPLVMLLFTLLVTWVAIDRLVL
HWLAELRKTTRSFARGDFGQRPNLAAAPQEIQELGGTLSRMADTIKAREAELEHTLSHRE
VLLKEIHHRVKNNLQIVSSLLSLQHRALPPGPARSALMQAQTRINALATVHRSLYETEDP
SLVDLGRFLRELGQLIYDGMGGLNGIVDLDIRIDGAVLVTSDQAVPLSLVMTEALTNALR
HAYPDGRSGVIRVRLGALDAEETLAAADATEATGTLGRPTHCLSVEDDGIGLAAEVSPID
SAQGEGTWTTIGLGRRGIGATLIRSLARQAGGRVTIGLREGGGTRVSLAFAAARPAPPPA
AS