Protein Info for Rru_A3230 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 594 PF00563: EAL" amino acids 19 to 238 (220 residues), 67.5 bits, see alignment E=1.9e-22 PF00571: CBS" amino acids 283 to 323 (41 residues), 23.4 bits, see alignment 9.1e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 407 to 491 (85 residues), 42.6 bits, see alignment E=2.6e-15 PF00990: GGDEF" amino acids 408 to 515 (108 residues), 51 bits, see alignment E=2.2e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3230)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPC0 at UniProt or InterPro

Protein Sequence (594 amino acids)

>Rru_A3230 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) (NCBI) (Rhodospirillum rubrum S1H)
MTVQASCVADLSSLGRDVALDPVISLRSGRVIGYQAVAGPPPGGREEDDLLLREAIEAAV
WSSAIALFAAVSAGRDQRLFLGLDFGLVVRWPDMAARLAMLLDAHGVDRRVITLSLSERR
SILDLGGGSGERALDRVAGAVVQMRGAVGSIALDGFGGGHAGLALLAAVKPDYVVLDPYF
VSTQAIDQTRRLFLGHLVDVAHLLGAQVIAPQVEHLADYHACRDAGCDLVRGPVLAKPDR
DPRRLPEVYPQVAALNATSQRRGRGDQHLVAAQMDEIDPLMISTKMADVFERFRRQKDRT
FFPVVDERGEPLGIVREVDLKEYTYSLYGKDLIGNKALGRTLSAFLTRCPRVDIDTRAEK
ILEAFSTTPSSDGLIITQDGRYRGFLTAASLLRVINDKNLEVARDQNPLTRLPGNTVINT
ELGEILADDRQGASLVYLDFDHFKPFNDKYGFRQGDRAILLFADLLRSQLAEAGFFIGHV
GGDDFFAALREGVPAAVTARIRALIDKFAADVTAFYDDETRQAGCVLARDRDGIERRLPL
LSVSAALVHLAPGHAIGDLDRIGGVIARLKKAAKQSPCHLAETVAGPDILVEEL