Protein Info for Rru_A3166 in Rhodospirillum rubrum S1H

Annotation: extracellular solute-binding protein, family 5 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 615 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00496: SBP_bac_5" amino acids 109 to 515 (407 residues), 239.9 bits, see alignment E=2.6e-75

Best Hits

Swiss-Prot: 43% identical to Y3691_BRUME: Putative binding protein BMEII0691 (BMEII0691) from Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)

KEGG orthology group: K13893, microcin C transport system substrate-binding protein (inferred from 100% identity to rru:Rru_A3166)

Predicted SEED Role

"ABC transporter, periplasmic substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPI4 at UniProt or InterPro

Protein Sequence (615 amino acids)

>Rru_A3166 extracellular solute-binding protein, family 5 (NCBI) (Rhodospirillum rubrum S1H)
MRPIAAVTLAALLALPLPLATVQAAETASSGPMHALSLYGDIKYPADFTHFDYVNPEAPK
GGAIRLSAFGTFDTLNPYTVKGTAAFGIGLTQTTLTVPSADEPSTEYGLVAQTMELAADR
SWLIFTLRPEARWSDGQPITAEDVAFSFQILKDKGQPLYNSYYSNVTGVEVLDAKRVKFT
FSPGENRELPSIVGQLPVLPKHYWATRDFAETTLDQPVSAGPYRIASFEPGRQITYERVK
DYWAEALPVSKGMNNFDRIRYDYYRDVTVTLEGFKAGAFDFNSEHSAKNWATEYKFPAVS
EGHVITEKVPVKGPDREQGFIFNMRRAQFQDPRVREALAYGFDFEWTNQTLFYGQYTRTR
SFFENSELAAVGLPGPEELKILEPLRAQIPPRVFTEEYQPPVTDEAKGGLRANLKKALDL
MKEAGWTVNAAGKMVNAAGQPFTFEILLRQADVERMVLPMVKNFERLGITATVRTVDTPQ
FISRVQSFDFDMVSAVWAQSNSPGNEQRDLWSSTAADIPGTSNLAGLKSPAVDSLIESVI
AAPTRADLIARTRALDRVLQWSFPWIPHYYGAFERIAYWNVFGRPAVTPNRGVVFQAWWF
DAEKAAKVVGRKGGF