Protein Info for Rru_A3159 in Rhodospirillum rubrum S1H

Annotation: General substrate transporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 38 to 60 (23 residues), see Phobius details amino acids 72 to 92 (21 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details amino acids 144 to 164 (21 residues), see Phobius details amino acids 180 to 200 (21 residues), see Phobius details amino acids 233 to 255 (23 residues), see Phobius details amino acids 275 to 295 (21 residues), see Phobius details amino acids 306 to 326 (21 residues), see Phobius details amino acids 332 to 355 (24 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 398 to 417 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 2 to 209 (208 residues), 73.3 bits, see alignment E=1.9e-24 amino acids 269 to 424 (156 residues), 31.6 bits, see alignment E=8.7e-12 PF07690: MFS_1" amino acids 40 to 383 (344 residues), 84.1 bits, see alignment E=9.6e-28

Best Hits

Swiss-Prot: 54% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3159)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPJ1 at UniProt or InterPro

Protein Sequence (428 amino acids)

>Rru_A3159 General substrate transporter (NCBI) (Rhodospirillum rubrum S1H)
MASLVGTTIEFYDFYVYATAAVLVFPHLFFPAGNEKTALLASFAVFGAAMGARPLGAVFF
GHLGDKRGRKITLVGALLTMGIATFLIGVLPTYASVGWIAPAMLVVLRLAQGFALGGEWS
GAALVATENAPAGKRAIFGTFPQLGAPIGFIIANGLFLIIAVLLPSSDPSKPSEAFLDWG
WRIPFLFSAVMVIFGLWVRLHLVESTAFEKTVKKGAVHSVPLVAVFRTHGKELVLGTFYM
LATYVLFYLMTTFSLSYGRASATAALPGLGYDYRTFVLMMIAGVVFFGLFTLLSGPWAER
WGRRKTLIGITLGIVVFGFLWVPMLGAGFVGVMAWLILGFTLMGMTFGPMGALLPELFPA
NIRYTGSGISYNVSSILGAALAPFVAVALWSAGDGSPFWVGIYLSGMASLTLLALVLGKE
TKDIDIEA