Protein Info for Rru_A3137 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 855 TIGR00229: PAS domain S-box protein" amino acids 38 to 159 (122 residues), 32.5 bits, see alignment E=8.1e-12 amino acids 161 to 285 (125 residues), 55.5 bits, see alignment E=6.5e-19 amino acids 285 to 408 (124 residues), 48.8 bits, see alignment E=7.3e-17 PF08448: PAS_4" amino acids 46 to 153 (108 residues), 38 bits, see alignment E=6e-13 amino acids 170 to 282 (113 residues), 26.2 bits, see alignment E=2.8e-09 amino acids 294 to 404 (111 residues), 33.6 bits, see alignment E=1.4e-11 PF13426: PAS_9" amino acids 52 to 151 (100 residues), 10.9 bits, see alignment E=0.00016 amino acids 176 to 279 (104 residues), 24.6 bits, see alignment E=8.9e-09 amino acids 299 to 401 (103 residues), 38.4 bits, see alignment E=4.5e-13 PF13188: PAS_8" amino acids 165 to 211 (47 residues), 24.1 bits, see alignment 9e-09 amino acids 292 to 336 (45 residues), 23.3 bits, see alignment 1.7e-08 PF00989: PAS" amino acids 165 to 277 (113 residues), 26.7 bits, see alignment E=1.7e-09 amino acids 296 to 399 (104 residues), 25.4 bits, see alignment E=4.2e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 411 to 572 (162 residues), 141.6 bits, see alignment E=2e-45 PF00990: GGDEF" amino acids 413 to 569 (157 residues), 161 bits, see alignment E=7.7e-51 PF00563: EAL" amino acids 591 to 824 (234 residues), 238.1 bits, see alignment E=3.2e-74

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3137)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPL3 at UniProt or InterPro

Protein Sequence (855 amino acids)

>Rru_A3137 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI) (Rhodospirillum rubrum S1H)
MVQVPPPPPTGFADHASAAEDREAGDGPAPSIAEGLSAALFQSVVEALPVGTALLRDGVI
VHANATLAGQIGETIDTLIGSPLTSYLTPADALAVQKVVEGAIALHGGVPVRRIAHIRHI
SGSERVYSLRFSPLDNGPHPLLVVITRDMTAQVAAENALRAAEGKYRAIFENAVEGIYQS
TPDGTYLDVNPALARIYGYASPAELIAHFTDIASQLYVDGTKRGEFQRLMRETGEVRDFT
AEVWRCDGHTIWITENARCVRGPDNEVLYYEGTVEDITAQRQSQETMRLLGKVFTSIAEG
IVLLERDLTVRTVNPAFEAMTGLLRQDMEGRPARLFASGLHENDFLATVAAEVDRAGLWR
GEIWGERREGPPYSGEMTVTAVRTRAGETTHYVAAITDITKRKRDEEHIRFQANFDMLTH
LPNRHLIMDRLEQAMHQAQRTGRQVCVMFLDLDRFKQINDSYGHSAGDEVLKLTARRLRN
CVRISDSVGRLGGDEFIVILSNVEDQHAGAYIAEKILYSLSEPFPIGGTEVFCIPSVGIT
YFPDHGETAPDLLRNADVAMYHAKQGGERRYAIFTPDMARRSLALLTMESDLRHALARDE
FELHFQPKVRADLTLIGAEALIRWRHPEKGLINPGDFIPLAEESGLILPIGRWTLREACD
RVMSWRAEGLTIPSVSVNVSPRQFQDQTLVETVRQILVETGLEPEALDLEITETVMTGDV
EHAVGTLRALKDLGVTLSIDDFGTGYSSLNYLKTFPIDTLKIDQTFVRDVLHSGKDAAIV
STIIALARNLGFSVVAEGVEEIEQAEFLGSRDCQNFQGFLYSRPLPPAEFTTFLRTAKLE
TATPPDLVPSIAPGP