Protein Info for Rru_A3132 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 493 PF01590: GAF" amino acids 27 to 172 (146 residues), 35.7 bits, see alignment E=1.8e-12 PF08447: PAS_3" amino acids 205 to 295 (91 residues), 29.2 bits, see alignment E=1.3e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 308 to 475 (168 residues), 133.1 bits, see alignment E=4e-43 PF00990: GGDEF" amino acids 312 to 473 (162 residues), 127.1 bits, see alignment E=8.8e-41

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3132)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPL8 at UniProt or InterPro

Protein Sequence (493 amino acids)

>Rru_A3132 Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain (NCBI) (Rhodospirillum rubrum S1H)
MSADRLLTCLAECSTRLDGADTWPVLMKQILALVGEASGATRTWVFQTITLTDQHVIQDH
LFEHISEDCWQLQLRKRFRLFRTALSAPDYHDLVRDRQRGLPSLLVTAEIAPGFLKASLE
RQKTAAMLSAPILVEGQWWGTIGLDDCQGGADWNATTIKFLQTIAGLIAGSIHRERQRVR
SQQVAVMERTTGGGLWELDVLRGDVWCSETLFHLLGYPPPCARLTIRRLLRHILPEDRAL
VMASARRCMREGLPAFRLDVRAWRHDRTLLWWELIIDVTETRPLDGFPLRMTGIVLEVND
RKTQELELARTAATDPLTGLANRRSFEALATRLLENKPGSGTLLVIDIDLFKHINDCFGH
AAGDEVLRHLAIVGRSVLRDGDLIGRLGGEEFAVLLQMDGPEAYAVADRLCQAVREMAVT
APSWEHSSVVVKITISIGIAHPCPFEDPKFALSEALRRADRALYGAKKRGRNQICHDTEG
RQSAISRDNRAKK