Protein Info for Rru_A3112 in Rhodospirillum rubrum S1H

Annotation: 4-cresol dehydrogenase (hydroxylating) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 transmembrane" amino acids 207 to 224 (18 residues), see Phobius details PF01565: FAD_binding_4" amino acids 47 to 183 (137 residues), 83.7 bits, see alignment E=5.3e-28

Best Hits

KEGG orthology group: K05797, 4-cresol dehydrogenase (hydroxylating) [EC: 1.17.99.1] (inferred from 100% identity to rru:Rru_A3112)

Predicted SEED Role

"FAD/FMN-containing dehydrogenases"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.17.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPN8 at UniProt or InterPro

Protein Sequence (532 amino acids)

>Rru_A3112 4-cresol dehydrogenase (hydroxylating) (NCBI) (Rhodospirillum rubrum S1H)
MLEDRVLTLHAFLEGARALLPPAAILFGEAVTPFLSSTSGHRRRVPLLVRPTNTGEVQAL
ARLATTCAVTLYPISKGRNWGLGSRLPGCEDCVILDLGGLDRINAIDERFGIAVIEPGVT
QAALADALAARGSAFFLDVTGSGRETSVLGNTLERGVAYNSLRAELVQSLEVVLADGSLL
RTGFAHYPTSRLGGLSRFAPGPDLSGLFVQSNLGIVVGGAVALLPRPERQMTFMVSVKDE
ARLPAFFDALRALRREGTLSSVVHVGNRRRSEITLTPLVHAEMAARGRDPTRAEAQKLTD
RFLTGRWSAIGSVMGPAAQVRVARRRIARALGGLGAVRFLSPGFRRFAKALSARIPGLGD
VNCFLCAVDPLLDLTSGRPTNAALHSTYWPHADQSEAAADPDRGPGGIVFAAPVVPLDGA
AVREAVDLTYELCRAHGFEAAITLNLMNDRTLEGVVSIDFRRDDPENLAAAHRCLRALNQ
GYVENGFTPYRVDIDSMDLVVDPADPFWATVSRLKQALDPAGVVAPGRYCPP