Protein Info for Rru_A3103 in Rhodospirillum rubrum S1H

Annotation: Multi-sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 34 to 54 (21 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 184 to 204 (21 residues), see Phobius details amino acids 217 to 240 (24 residues), see Phobius details amino acids 253 to 272 (20 residues), see Phobius details TIGR02916: putative PEP-CTERM system histidine kinase" amino acids 6 to 677 (672 residues), 615.9 bits, see alignment E=5.5e-189 PF13492: GAF_3" amino acids 312 to 444 (133 residues), 30.2 bits, see alignment E=8.1e-11 PF02518: HATPase_c" amino acids 577 to 679 (103 residues), 64.8 bits, see alignment E=1.4e-21

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3103)

Predicted SEED Role

"Sensory transduction histidine kinases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPP7 at UniProt or InterPro

Protein Sequence (688 amino acids)

>Rru_A3103 Multi-sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MVMVVGYCLACAAFLVLIVQAVSGRRRTGRERLVLAMPLVAGALWAGVTAARAVVPLPDW
AFVLAEIGRAACWIGLLAAIVLENRERRLLAVSLLTIVLGGGAVILHAALHDRDAFWSLT
LSSLLLYTIAGFVLLEQLYRSAREQQKWMIKHLSIALVCFFGFDLYFFSTALVMGGLDID
LLTARGYVAAFLALMATVSISRLNGHSERLHLSHGAAFQSMILVACGLYLVSMAAIGYYL
RHIGGAWGGPLEIVFFFATLALLGIGLSSGALRARLRVIVSKHFFKYRYDYRNEWLGFTA
TITGAGSEGLHERIVKAVAAIIESTGGALWTRSVEDGVLLPTARWNMGASPLPAIPLDSS
LCRYLQSQAWVVDLSEALTFPDRYPGLTLPDWLAEHPRAGLCVPLILREELQGVLVLGPL
RAPRKLVWEDLDILKTVGCHAAGYLSEERALNRLSDAQRLDAFNRRFAFVIHDIKNVVSQ
MCLMAKNAERFGDNPDFQKDMIATVVHSADRLQKLLQDLKAAGQTPDPAALSPAAVPLAE
VVREAGERWRALKPDLLVDLAPDWAPNSAIVCSGREMASVLDHLLQNAIDAVATTGGTVR
LSHREGGGQAIVEVADEGPGMEDAFIADGLFRPLNSTKSTGLGIGAFQCREIVRRMGGQL
TVTSDRGRGTRMTVLLPDRTAQARRGAA