Protein Info for Rru_A3057 in Rhodospirillum rubrum S1H

Annotation: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 159 PF08534: Redoxin" amino acids 4 to 156 (153 residues), 110.3 bits, see alignment E=7.6e-36 PF00578: AhpC-TSA" amino acids 4 to 137 (134 residues), 40.4 bits, see alignment E=2.6e-14

Best Hits

Swiss-Prot: 47% identical to PRX2_POPTR: Peroxiredoxin-2 from Populus trichocarpa

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3057)

MetaCyc: 53% identical to glutaredoxin-dependent peroxiredoxin (Arabidopsis thaliana col)
RXN-20687 [EC: 1.11.1.25]

Predicted SEED Role

"Peroxiredoxin"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.11.1.25

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPU3 at UniProt or InterPro

Protein Sequence (159 amino acids)

>Rru_A3057 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen (NCBI) (Rhodospirillum rubrum S1H)
MIAVGDALPSGTLHHKTAAGIEAVDPAEFLGAGKAVLFAVPGAFTPTCSDSHVPGYIAQA
QALRDKGVTKVACVAVNDAFVLAAWSKALGAEGTVEMLADGNGDYARALGLELDLTAKGL
GKRFQRCALVLDNGKVTHLAVDEGGALDVSSAEAVLALL