Protein Info for Rru_A3039 in Rhodospirillum rubrum S1H

Annotation: PAS/PAC Sensor Hybrid Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1067 transmembrane" amino acids 474 to 492 (19 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 397 to 505 (109 residues), 42.6 bits, see alignment E=3.1e-15 PF08448: PAS_4" amino acids 399 to 499 (101 residues), 28.5 bits, see alignment E=4.7e-10 PF13426: PAS_9" amino acids 409 to 497 (89 residues), 25 bits, see alignment E=5.9e-09 PF08447: PAS_3" amino acids 414 to 484 (71 residues), 36.5 bits, see alignment 1.5e-12 PF00512: HisKA" amino acids 536 to 603 (68 residues), 32.4 bits, see alignment 2.4e-11 PF02518: HATPase_c" amino acids 647 to 774 (128 residues), 66.5 bits, see alignment E=8.2e-22 PF00072: Response_reg" amino acids 811 to 920 (110 residues), 50.1 bits, see alignment E=8.8e-17 amino acids 942 to 1051 (110 residues), 52.8 bits, see alignment E=1.3e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A3039)

Predicted SEED Role

"sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RPW1 at UniProt or InterPro

Protein Sequence (1067 amino acids)

>Rru_A3039 PAS/PAC Sensor Hybrid Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MGQKEADIATAPTSETPWGDLFSQGGDMGRLMAAFPWDSSPLGPVSGWPSPLRTVVGMLL
RSKAQIVLFWGPHLVALYNDAYAPTIGGKHPRALGRPARENWGELWDTLGPMLGQVRLTA
RAFGADNYPFQINRHGFLEQVYFDISYDPVPGADGEVAGVFCTVTETTARVFAERRLAAL
RELSIALSTTLARSDGPLSLGEALPKAALAAIAGHLAQDVSRAAIYRHGSHGKPVLVATT
DPAPRTRPQATGTTEGSPFAEILERVRREGRPVLWEGGGDGGPQRLLGVPLTAEQGPMGV
LVVSVCPLVAADAEYRKVIDLAAGQISSALTTAAILERERERADDLTRVAADNARLYREA
QREIADRQAIEAQFLHLTDTLEKMVEERTGERDRLWRVSGELMAVGTADSHIKAVNPAWE
TLLGHDERLLVGAPMSLLVHPDDREPSTAALRAMEPQGPPLRFENRLRDSDGTYHWIAWT
IVAHGALFYMVGRDVTEEKQARDALAEAHRQLIAQTAERERAEEALRQAQKMEVIGQLTG
GVAHDFNNLLTIILGNLETLIRHIDGASPPDPARVRTLVERATLGAERAAALTQRLLAFS
RRQPLDPRPLDLNRLTLGLIDLLHRTIGEKIALDTRLSMVPVGVLADANQLESVVLNLAL
NARDAMPTGGRLILETTADLVIEAPTAEKRPAKGNPAGAPPGTYAALRVTDTGKGMEAGV
LARVFDPFFTTKDVGQGTGLGLSQAYGFIKQSGGHIGIESEPGQGTTVTILLPRLEGALP
LPEESDRDETPAALGGLEITPPPGDPSILLLVVEDDPSVRAHSTASLRELGYQVIEAGNG
AEALGHLAAHPDVALMFTDIGLPGGMDGRQLAELARRNRPDLAVVLTTGYARDALNGNVP
LAPRMALLTKPFSFTALALKVHEVLPPRPAPQSSAPQGPVTVLLVEDDPLVSLAAADLLL
SLGCAVDQAYSVADALAQASAATPDVAVIDIGLPDGRGDDLAQTLRQRLPGLPIVIASGY
DRSEIDARFGDDPRLRFLGKPYLDSQLEAALTGALGHPLERSTAPRA