Protein Info for Rru_A2997 in Rhodospirillum rubrum S1H

Annotation: Phosphate acetyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13500: AAA_26
  • amino acids 5 to 210 (206 residues), 70.9 bits, E=2.1e-23
• PF07085: DRTGG
  • amino acids 214 to 325 (112 residues), 79.7 bits, E=2e-26
• PF01515: PTA_PTB
  • amino acids 371 to 686 (316 residues), 411.5 bits, E=4.3e-127
• TIGR00651: phosphate acetyltransferase
  • amino acids 386 to 686 (301 residues), 419.1 bits, E=6.2e-130

Best Hits

KEGG orthology group: K13788, phosphate acetyltransferase [EC: 2.3.1.8] (inferred from 100% identity to rru:Rru_A2997)

Predicted SEED Role

"Phosphate acetyltransferase (EC 2.3.1.8)" in subsystem Ethanolamine utilization or Fermentations: Lactate or Fermentations: Mixed acid or MLST or Propanediol utilization or Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Threonine anaerobic catabolism gene cluster (EC 2.3.1.8)

MetaCyc Pathways

• L-threonine degradation I (6/6 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (4/4 steps found)
• pyruvate fermentation to acetate and lactate II (4/4 steps found)
• acetyl-CoA fermentation to butanoate (6/7 steps found)
• pyruvate fermentation to acetate I (3/3 steps found)
• pyruvate fermentation to acetate II (3/3 steps found)
• pyruvate fermentation to acetate IV (3/3 steps found)
• pyruvate fermentation to acetate VII (3/3 steps found)
• superpathway of acetate utilization and formation (3/3 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (10/13 steps found)
• acetate and ATP formation from acetyl-CoA I (2/2 steps found)
• superpathway of Clostridium acetobutylicum acidogenic fermentation (7/9 steps found)
• ethanolamine utilization (4/5 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (14/19 steps found)
• superpathway of L-threonine metabolism (13/18 steps found)
• sulfoacetaldehyde degradation I (1/2 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (6/9 steps found)
• mixed acid fermentation (11/16 steps found)
• (S)-propane-1,2-diol degradation (3/5 steps found)
• acetylene degradation (anaerobic) (3/5 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (11/17 steps found)
• methanogenesis from acetate (3/6 steps found)
• sulfolactate degradation II (1/4 steps found)
• heterolactic fermentation (11/18 steps found)
• L-lysine fermentation to acetate and butanoate (5/10 steps found)
• superpathway of sulfolactate degradation (2/6 steps found)
• superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
• lactate fermentation to acetate, CO₂ and hydrogen (Desulfovibrionales) (3/8 steps found)
• superpathway of N-acetylneuraminate degradation (13/22 steps found)
• gallate degradation III (anaerobic) (5/11 steps found)
• superpathway of taurine degradation (1/6 steps found)
• purine nucleobases degradation II (anaerobic) (12/24 steps found)
• superpathway of methanogenesis (3/21 steps found)
• superpathway of L-lysine degradation (12/43 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Pyruvate metabolism
• Taurine and hypotaurine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.8

Use Curated BLAST to search for 2.3.1.8

Sequence Analysis Tools

See Q2RQ03 at UniProt or InterPro

Protein Sequence (703 amino acids)

>Rru_A2997 Phosphate acetyltransferase (NCBI) (Rhodospirillum rubrum S1H)
MPARMFFLAPMAQDVGLTSVALGLARALQRDGIKVGFAKPIGHAEADGEPGDPSSHFARS
LCLLEAPESIAFARAEDQVRRGDLAALMEEVVTLVDGLRASHDAVIIEGLIPGADTQVAG
RLNAEMARALGADLIPVLSGAGRDGADLAEAIALARRQYDGAQNAAFAGVLINKVSPSHG
AELRGDLERAVGERLPILATIPFETRLQSPRLADVVRGLGLTVEHEGALAQTRVREIVIA
ARSVENIIERLRPGALVVTPVDRIDIVLAATLASLRGVPLAGVLLTCGGSLPDTVASLVL
SARPEGLPILSTPADTYATASRLSRLSGHVGADDHAQMEEVIDFIAEQIATAPLRRRIGE
PGEVRMSPPAFRNRLIQSARRAAKRIVLPEGDEPRTLQAAIACHAKGIARCVLLGHPAQV
RQVASAQGLEIPADLEILDPELVRGRYVEALVEMRRAKGLTALQAAAQLEDTVVLGTVML
ALGEVDGLVSGAVHTTASTVRPALQLIKTAPGASIVSSVFFMLMPDQVLVYGDCAINPNP
TAEQLADIAIQSADSALAFGIEPRVAMISYSTGSSGVGDDVEKVRAATALAKLKRPDLMI
DGPMQYDAASVESVGRQKAPDSPVAGRANVFVFPDLNTGNTTYKAVQRSANVVSVGPMLQ
GLRKPVNDLSRGALVDDIVYTIALTAIQADQGADPMAEKVAAE