Protein Info for Rru_A2942 in Rhodospirillum rubrum S1H

Annotation: ABC transporter, transmembrane region (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 transmembrane" amino acids 35 to 59 (25 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 179 to 197 (19 residues), see Phobius details amino acids 258 to 280 (23 residues), see Phobius details amino acids 292 to 309 (18 residues), see Phobius details PF00664: ABC_membrane" amino acids 39 to 308 (270 residues), 146.4 bits, see alignment E=1.5e-46 PF00005: ABC_tran" amino acids 372 to 521 (150 residues), 103.5 bits, see alignment E=1.4e-33

Best Hits

Swiss-Prot: 39% identical to MSBA_DESPS: Lipid A export ATP-binding/permease protein MsbA (msbA) from Desulfotalea psychrophila (strain LSv54 / DSM 12343)

KEGG orthology group: K11085, ATP-binding cassette, subfamily B, bacterial MsbA [EC: 3.6.3.-] (inferred from 100% identity to rru:Rru_A2942)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ56 at UniProt or InterPro

Protein Sequence (605 amino acids)

>Rru_A2942 ABC transporter, transmembrane region (NCBI) (Rhodospirillum rubrum S1H)
MTTRTAREAGEAEAAGPSTLRLVGRLIKDHLAQQWGLIALAVLCMLAVAASTSAIAWLMK
PAVNDVFARHDRDVLMLIALAFPVAFVLKGLANYGQRTLMNRVGLRVVQRCREALYDHLQ
GMDIAFFAQQQTAALVSRFTVDLTLLKNTITSGIMVVGRDAVTMVSLVVSLFLLDIELAL
IAVTVFPAAVLPIALLGKRVRKAARGMQAQSGQLDALLLQVFQAIRVVKVYNAGEHERAR
VAATVDRIYRHLMRSERIGAAISMVVEILSGFAFAAVVIYGGQRVTAGDLDPGTFFAFIT
SLFLLYQPIKRIGGVNVVAQEGMAAVERMYGVIDTPPALREGKDAPALVVGGGEIVFDDV
RLTYPTQEGPALDGLSFRAPAGATVALVGRSGAGKSTALQLVPRFYDADGGRVLIDGQDV
RAVTFRSLWAAIAMVTQEIILFDDSVRANIAYGRPGASQAEIEDAARHAAAHDFILALPE
GYDTVIGEQGTRLSGGQRQRLVIARAMLKNAPILLLDEATSALDTESERHVRQAFERLRQ
GRTCIVVAHRLSTVMNADIIHVIDAGRIVESGSHAALLAEGGLYADLCATDLSDEPAEDP
EVVPA