Protein Info for Rru_A2940 in Rhodospirillum rubrum S1H

Annotation: Glycine cleavage T protein (aminomethyl transferase) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 PF01571: GCV_T" amino acids 23 to 125 (103 residues), 30.4 bits, see alignment E=1.2e-11 TIGR03317: folate-binding protein YgfZ" amino acids 175 to 240 (66 residues), 82.4 bits, see alignment E=8.4e-28

Best Hits

KEGG orthology group: K06980, (no description) (inferred from 100% identity to rru:Rru_A2940)

Predicted SEED Role

"Folate-dependent protein for Fe/S cluster synthesis/repair in oxidative stress"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ58 at UniProt or InterPro

Protein Sequence (312 amino acids)

>Rru_A2940 Glycine cleavage T protein (aminomethyl transferase) (NCBI) (Rhodospirillum rubrum S1H)
MTPADPSAVSPPVLCPRPDRGVLGLSGADRVSFLQGLVSNDVTRAGPEQALWAAFLTPQG
KYLHDFFVVSVGEGESARLLLVGEAARLEDLRARLSRYRLRSKVTLDLAGGWTVAVIPGR
NAAASLGLPDRPGAMRALDGGGLAFVDPRLSAAGVHLLLPEAAAKPPLPLGEESLWQAHR
LALGLPEGSDDLEPEKALLLENGFEELGGVDFKKGCYMGQELTARTKYRGLVKKRLIPVA
IDGPLPAPGSALRTGEGLDAGEMRSGLVRADGQTLGLALLRLARLGGPILAEDGGATLTP
SIPSWMIIPTAE