Protein Info for Rru_A2914 in Rhodospirillum rubrum S1H

Annotation: Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 533 signal peptide" amino acids 17 to 17 (1 residues), see Phobius details transmembrane" amino acids 18 to 39 (22 residues), see Phobius details amino acids 229 to 249 (21 residues), see Phobius details PF00512: HisKA" amino acids 313 to 371 (59 residues), 30.2 bits, see alignment 3.7e-11 PF02518: HATPase_c" amino acids 420 to 529 (110 residues), 92.6 bits, see alignment E=2.2e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2914)

Predicted SEED Role

"Sensor protein basS/pmrB (EC 2.7.3.-)" in subsystem Lipid A modifications or Orphan regulatory proteins (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQ84 at UniProt or InterPro

Protein Sequence (533 amino acids)

>Rru_A2914 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MALKLPRRLLPRSTTLRIALSFLVLFGGASGLLMAGVYWTTSRFLMFQVDGVIGDDIALL
TNAARERGHRLLAAMLVTRARQAGEAQAVYLLADQDGEPLAGNLATWPEGLEATGWTILP
ATALTVVPVTDTLPPPPRRPDRPEDSERRQRHREAWDDWRPPLPDSLPPPPPRLFADRGG
RDPADPDVRPRPWRRGDVRVAALTLPSGMRLLIGRDLGPIQALRHRMAGAMRLGLGGMVV
LGLAGGLVMSRRFSRRLEAVNRTSREIIGGDLSRRVPQGRGLDGDDFDQLAVNLNAMLGR
IETLMEGVRHVSDTIAHDLRTPLSRLRNRLERLQADAQCTDRDELAAALAEVDSLLATFH
ALLRIAQVETGGRRMAFSPVDLLALLIDVAELYDAVADERTVTLDLDLALAPGARLLVDG
DRDLLFQAFANLLDNAVKYSPEGGRVSLALIRGETRVTISLRDQGPGIPAADRQRVFERF
ARLDTARTTPGNGLGLTMVGAVIEAHDGTIALEDAPGGGLLVRVVLPLRRGPG