Protein Info for Rru_A2881 in Rhodospirillum rubrum S1H

Annotation: virulence protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 456 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF06057: VirJ" amino acids 47 to 139 (93 residues), 22.8 bits, see alignment E=3.9e-09 amino acids 258 to 447 (190 residues), 254.4 bits, see alignment E=3.7e-80

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2881)

Predicted SEED Role

"Type IV secretory pathway, VirJ component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQB7 at UniProt or InterPro

Protein Sequence (456 amino acids)

>Rru_A2881 virulence protein (NCBI) (Rhodospirillum rubrum S1H)
MIRLRIIVPLVALTLLGIGFAATHTKQFTTGSLPDPKIEMPKGPQNALVVLISDAQGWSD
EDDRLSARLKDSGSVVVGIDLPRYLAILEKDPEDCVYLVGDIEELSQEVQKAAGGSAYVL
PVIAGSGEGADLALAMAAQTPDATIGHTLAVDPTGGLPLKKILCTDAPHRTTTAGIAYGL
QTGPVPNPIDTLFTPAAPAPGRDHVASLRETWGAITATETTQPAKAALETALMALLTDPS
AKTKDAWATELPTTATRDTLAIVYSGDGGWRDLDKEIADEFQKRGVPTLGVDSLRAFWSR
KTPEETAKTLSRLINTYTRRWQVNKVLLVGYSFGADILPATLAALPEADRARITQISLLG
FSTEANFEISVTGWFGAKHGESQPTLPDLAKLDPAQIQCFYGLEEDDSACPKLKDSGIEI
LSTTGGHHFDGDYKALATRILAGLDRRAALAEAEGK