Protein Info for Rru_A2874 in Rhodospirillum rubrum S1H
Annotation: FAD dependent oxidoreductase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00301, sarcosine oxidase [EC: 1.5.3.1] (inferred from 100% identity to rru:Rru_A2874)Predicted SEED Role
"COG0665: Glycine/D-amino acid oxidases (deaminating)"
MetaCyc Pathways
- creatinine degradation I (2/4 steps found)
- glycine betaine degradation I (4/8 steps found)
- creatinine degradation II (1/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.5.3.1
Use Curated BLAST to search for 1.5.3.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RQC4 at UniProt or InterPro
Protein Sequence (435 amino acids)
>Rru_A2874 FAD dependent oxidoreductase (NCBI) (Rhodospirillum rubrum S1H) MSGSSPTPASPSSTPPSLWAATAPSAPPTRTLAGETRADLAVIGAGVTGLSTALHAAEAG LTVTVVEAEEAGFGGSGRNNGQVIPTLAKPDPSDLVAKWGEAGERLARMVGESAALVFDL IDRHAIACEAVQHGWLQPAHRPSRLTVSQKRHREWTARGLDCRLVDRAETAALTGSDYWA GGLLCPTGGHVTPLALTRGLARAAQKAGATVYTASPVTGIDRRGSDWRVATPGGAVTARA VVIATSAYGQGVWPTLERSIVPVRNFQMSTQPLPPEVLAKVIPADVAISDTHGDLYFFRK TADGRLVSGCTLTSRTSDPTEAKARVIARILEVFPQAGRQTIDYCWHGQLDFTPDFHPRF YSLEPGIFAAIGYNGRGLALGVAVGRELARAAAGTPFSQLALPDGGKPRPLPFHGLITGV APLMMHWWRHKDGRD