Protein Info for Rru_A2763 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 175 to 195 (21 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 249 to 368 (120 residues), 56.2 bits, see alignment E=3.9e-19 PF13188: PAS_8" amino acids 251 to 303 (53 residues), 31 bits, see alignment 5.3e-11 PF00989: PAS" amino acids 251 to 320 (70 residues), 36.5 bits, see alignment E=1.3e-12 PF08448: PAS_4" amino acids 256 to 366 (111 residues), 29.2 bits, see alignment E=2.8e-10 PF13426: PAS_9" amino acids 260 to 364 (105 residues), 38.7 bits, see alignment E=3.1e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 373 to 537 (165 residues), 148.6 bits, see alignment E=1.4e-47 PF00990: GGDEF" amino acids 376 to 534 (159 residues), 145.9 bits, see alignment E=2.8e-46 PF00563: EAL" amino acids 560 to 791 (232 residues), 212.7 bits, see alignment E=1.6e-66

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2763)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQN5 at UniProt or InterPro

Protein Sequence (820 amino acids)

>Rru_A2763 Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI) (Rhodospirillum rubrum S1H)
MRSISQSLRGRFLLTALVLAIVLLGISAYGQSLVKAIGAESHRQIQTYYGSHRLLQETKT
ALGQVERALHEAMIHPDAIGSVRAAVAGLRAAVGRLTSDPTLAGQPIFSGLPAAVDEMST
RLDRDLGRWSRGEAAAPVGLVDGLRDVLHLCERRVYDAMVDKTYLALGTSDTLSIIIWGL
TGVIFLIVLAAYGVFELSIRRPVLRVAEALRAEGRGAVGETDVPMPRTIETWLLVDAFNG
MRLQVHSRQLRLQSVLESTSDGIITVDDKGSIESINGAAERVLGLTRDEAVGRPLGDLIP
LDRLAEDGGEEGALSRRLLALRGREIDLPARRADGAAFHLSLKLSDFMLGERRYFNALIA
DVTDRKAMIDRLTFLAQRDPLTGLINRRSFFDDLEKAVARAGRFPAAGVAVISIDLDRFK
YVNDSLGHQAGDCLLKEVAEVLFGRLRETDLLARLGGDEFAVLLHGVNREGALHVAEALR
LCLADYAFSYDGKSVEIGCSLGVATWAADVDDPEDLLARADMAMRLAKRAGRNRVHLFEE
GDLEVRARVVADAGYSKLIDRGLRNNLFRPVFQPIIDVTSGAVVGHETLARLHDPAAIGL
TMDVLIPVAERFGLAVEIDRQIILAVTEALAEDAGWLEGGFLSFNLSAQSVGDGRIFSAV
RRLIATRRLPPQALIFEITETAAIASLAAARTFLKALTDLGCKTALDDFGSGYSSFTYLR
ELPVDFLKIDGRYVRDIHHDPVKAAMVQAINTVAHAMGMRTIAECVEEASGLEVLRQSGV
DCAQGFLFGRPAPLGPWIVPNPIPKGIGRPRLALVAPEGR