Protein Info for Rru_A2719 in Rhodospirillum rubrum S1H
Annotation: Indolepyruvate decarboxylase (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K04103, indolepyruvate decarboxylase [EC: 4.1.1.74] (inferred from 100% identity to rru:Rru_A2719)MetaCyc: 64% identical to phenylpyruvate decarboxylase (Aromatoleum aromaticum)
Phenylpyruvate decarboxylase. [EC: 4.1.1.43]
Predicted SEED Role
No annotation
MetaCyc Pathways
- L-phenylalanine degradation III (3/4 steps found)
- L-phenylalanine degradation II (anaerobic) (2/3 steps found)
- indole-3-acetate biosynthesis VI (bacteria) (2/3 steps found)
- L-tryptophan degradation VIII (to tryptophol) (2/4 steps found)
- anaerobic aromatic compound degradation (Thauera aromatica) (3/27 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 4.1.1.43 or 4.1.1.74
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RQS9 at UniProt or InterPro
Protein Sequence (553 amino acids)
>Rru_A2719 Indolepyruvate decarboxylase (NCBI) (Rhodospirillum rubrum S1H) MPTIATALLDALKAHGATRIFGIPGDFALPFFRVAEQSALLPLYTLSHEPGVGFAADACA RMGRGLGVAAVTYGAGALNMVNPVAGAWSEKSPLVVISGAPGVAESAGGLLLHHQAKTLD SQWRIFEEITCARTRLDDPLTAPGEIARVLRACLEHSRPVYIEIPRDIVDAPCAAVDRLP PTPVDGEAVEAAAGEIMARLAAASAPALLLGVEVRRHGIEADVAELARRLGLPIATTFMG RGLLSEEGAAGGAPDSLMGTYLGLAGRPEVRAVIEDSDGLLMLGVILSDTNFGVSGKRID LRRAMLAADRQVALGFHTYNDIPLADLVAALLRQAEGFARQDAKALPKPTALPRDMIADG APIGPMDIAAAINDLFSAHGVMPIASDMGDCLFTALDTTHAPLVAPGYYATMGFGVPAGL GVQASCGRRPLILVGDGAFQMTGWELGNCARYGWDPIVIVFNNASWEMLRTFQPDTAYND LADWRFADLAAGLGGVGHRCQTRADLARALDRAAREPGRFHLIEAVLARGAISDTLQRFV TTMKGRHAAAADA