Protein Info for Rru_A2635 in Rhodospirillum rubrum S1H

Annotation: Transcriptional Regulator, Crp/Fnr family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 PF00027: cNMP_binding" amino acids 35 to 113 (79 residues), 43.2 bits, see alignment E=3.1e-15 PF13545: HTH_Crp_2" amino acids 150 to 228 (79 residues), 45.6 bits, see alignment E=5.4e-16

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2635)

Predicted SEED Role

"cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RR13 at UniProt or InterPro

Protein Sequence (252 amino acids)

>Rru_A2635 Transcriptional Regulator, Crp/Fnr family (NCBI) (Rhodospirillum rubrum S1H)
MTPEHKDKALAAVSFFDRLPAPRRAELAAKAEAAQLPAGFPLAERGVPATGLQVLVEGQV
RLFLPPEESTIDIVGPGSLLGECALCDDARHPVSAQAISPVVILDLRAEDVWPVLLAETD
ATLALLGAISANLKGLLGRVNDIKLRTTAQRLAMFLVSLARQPSAVDRAANGPAEGIILT
LPYGKKLIAERLAMTPESLSRSLARLGREGVRAVDRTTVRIDDLDALALFAGLLPEEEND
DDALHRAQGYWR