Protein Info for Rru_A2597 in Rhodospirillum rubrum S1H

Annotation: Iron permease FTR1 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 34 to 58 (25 residues), see Phobius details amino acids 70 to 90 (21 residues), see Phobius details amino acids 127 to 151 (25 residues), see Phobius details amino acids 157 to 178 (22 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 253 to 272 (20 residues), see Phobius details PF03239: FTR1" amino acids 1 to 262 (262 residues), 214.7 bits, see alignment E=8.9e-68

Best Hits

KEGG orthology group: K07243, high-affinity iron transporter (inferred from 100% identity to rru:Rru_A2597)

Predicted SEED Role

"Ferrous iron transport permease EfeU"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RR51 at UniProt or InterPro

Protein Sequence (290 amino acids)

>Rru_A2597 Iron permease FTR1 (NCBI) (Rhodospirillum rubrum S1H)
MLAPFLIMLREGIEAALLTSIIAGYLKQTGRGAWLPAVWVGVLLAVALSLFAGTLLQMMA
AEFPQKAQELFEAIVGLVAVTVLVSMVFWMRKAARSIQTDLRGAIDAALKEPAGEPGTTA
PVSAAWPLIGMTFFAVGREGLESVFFLLAIFQQSPGPLAPIGALLGLVVAVGLGVALYRG
GIRLDLRRFFRWTGVFILIVAAGLASASLRSLHEAGLWNHLQARAYDLSDTLPVSSVLGT
VLSGVFNYQDAPAIGEAIVYGLFLLTTLIVFLKPPRPAPLRRAAPDSLKG