Protein Info for Rru_A2553 in Rhodospirillum rubrum S1H

Annotation: Methylase involved in ubiquinone/menaquinone biosynthesis-like (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 PF05175: MTS" amino acids 8 to 119 (112 residues), 25.7 bits, see alignment E=2.9e-09 PF13489: Methyltransf_23" amino acids 10 to 126 (117 residues), 48 bits, see alignment E=4.2e-16 PF01209: Ubie_methyltran" amino acids 18 to 121 (104 residues), 22.9 bits, see alignment E=1.7e-08 PF13847: Methyltransf_31" amino acids 21 to 136 (116 residues), 38.8 bits, see alignment E=2.7e-13 PF08242: Methyltransf_12" amino acids 23 to 117 (95 residues), 40.9 bits, see alignment E=1e-13 PF13649: Methyltransf_25" amino acids 23 to 115 (93 residues), 66.6 bits, see alignment E=9.5e-22 PF08241: Methyltransf_11" amino acids 23 to 119 (97 residues), 69.5 bits, see alignment E=1.1e-22

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2553)

Predicted SEED Role

"COG0500: SAM-dependent methyltransferases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RR92 at UniProt or InterPro

Protein Sequence (229 amino acids)

>Rru_A2553 Methylase involved in ubiquinone/menaquinone biosynthesis-like (NCBI) (Rhodospirillum rubrum S1H)
MTKPRGNTEVLLEALPPAGRALVDVGCGDGALARVLAAKGARSVLGFDVADRQLALALAA
PTVAGVAYVKAGAQAMPLAEASVDGVIFFNSLHHIPQPLMARALGEAARVIRPGGLIYVA
EPIAEGPNFEMLRPLDDETQVRAQAQACLDGAEDLGLRRLRSFAYRTRIRRASFDEIRLR
FTAIHSDRDQAFAAVEPALRLSFERLGVEDGTGGRVFDQPMRAALFTRP