Protein Info for Rru_A2521 in Rhodospirillum rubrum S1H

Annotation: DNA helicase, putative (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1697 PF13086: AAA_11" amino acids 430 to 547 (118 residues), 45 bits, see alignment 5.4e-15 amino acids 1128 to 1170 (43 residues), 33.5 bits, see alignment (E = 1.7e-11) PF13604: AAA_30" amino acids 430 to 531 (102 residues), 35.1 bits, see alignment 5.2e-12 PF13245: AAA_19" amino acids 449 to 531 (83 residues), 28.8 bits, see alignment 5.7e-10 PF13087: AAA_12" amino acids 1262 to 1378 (117 residues), 43.9 bits, see alignment 9.3e-15 PF18741: MTES_1575" amino acids 1422 to 1514 (93 residues), 95.8 bits, see alignment 5.8e-31 PF04480: DUF559" amino acids 1434 to 1512 (79 residues), 32.1 bits, see alignment 3.9e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2521)

Predicted SEED Role

"DNA helicase, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRC4 at UniProt or InterPro

Protein Sequence (1697 amino acids)

>Rru_A2521 DNA helicase, putative (NCBI) (Rhodospirillum rubrum S1H)
MDALAKTKKDLGNLLRYTEELLSFNDKVVFDLTREKYPRFPEHVVVGLEGVDIAVDAETW
VRARRLRETPPPPCDAMFDGWVDVASHPSPNTPPKLVAERMLTLPIEEISDLAEAGLLPD
LEDVMVPVKADTALPERMDVILRTANMVDFRRLWQDYIDGPWTAWAQVERPRRQAIDFYN
KIYAIHLSLLSMGDDTPIELVFGAGMARWATKTERVSAPLIEQLVETELEEDGTLLIRPR
RTLPHLALRPFHALEIEGCKAIERDIGAQFDALVDDPDRGFTPFDTSSFESVLRVCAARL
SATGIYHPDTLGDPGDRTLPAVDGFLRITDTWVLYVRPRGEDIRKDDISRLIKKLDAVTD
ESDLPRPARGFVEAPSDTLPFAGEDSLIDLSGADFDLPDRALSRSLAPGAGEAFQGVRPA
EEIHFFPLPYNDDQQEIIRRLQDDDTVGVLVQGPPGTGKTHTIANIICHYLATKRRVLVT
AKTPEALTALQEKIPEGIRDLAIAVIHNDREGARQLENAVRILADEAKSINPRIVNEEIR
EKQARIASLRETIATVDRQLLAFANHNLAPMAYGDDTALPMEVAKAVVEESPRHLWFEDR
LTTQARHQPRFSEADIAEIRALRHRHAGDLAYPHEALPKPADLPELARVLAAHRGLARIN
EIEAYANAGEIPALSLDNAIGLDGAQTLAEWLQDLGETLNDLESEGWLFDVYHGLLGLRR
MDERALASLKVVLSNWIALCERGRGFALKGVILEGGAEDPAFDKALEDLAAGRNPFGVFS
LFKGGLKSRIEAVRLEGHPPATREDWATIQAYRVWRQQLGLFLGRWNAIAQALDLPPLPA
EGRGAESAVLRLGGLVERVWRLHEEVEPCRDALRLLFPYDLDIDEALYHGRTARLAEALA
VNLEKADLADAETVKAEGLAIAQDLPLPFHAALRAICHSLGLTDIPQTAIAEAWRSILSE
AVRLEAIADDIARLDALVGKVSASGAPLWAAKLRTEPPRGGDDPWTPDDWRKSWDWARAK
GHLRSLGDRETVRALSEDRARAEAEQRKLFAELVRLRTFLGLKLGMSNKVEAALAKFGAA
IARLGKGTGKSAGRQRRIIREAAMETAQAVPCWILPEWRVAEQLPPDLAAFDLVIIDEAS
QSDITALPAILRGKKVLIVGDDKQVSPTIIGLNDRKIIQLRTTFLSGLPFADQMDPATSL
YELGGMVFPGKAVMLREHFRCVEPIIRFSSGFYPTPLIPLRLPKASERLDPPLIDIYVPH
GRKTGEINRAESDVIVDEITKLTQDPAFQRRSIGVISLIGSAQARLIYERLVRDLGTEVI
EKHRILCGSSATFQGQERDIMFLSMVACPETAIMQAERKWEQRFNVATSRARDRLVLVRS
VAASHLKPGDLKARLIEHFRNPMAAGKVIEPTEVLDLCDSGFERDFGRCLLDLGYRLKPQ
VPVGGYRIDFVVEGADDRRLAIELDGDKYHGPDRWAHDLRRQKALERLGWIFWRCWGSSW
ISDRQGCLDDLKATMTRLGIEPLGMAGAGDVHTLHIEVARPAIASEPPPADLVEAPPTPT
EAPLPTPGIGLDLGDGAVLAEGEEIFCFLHKKDAGTRPANGVAVARGGALHMNDAPLTPQ
RRGAWLQAALVVVQKAANDLNPTTGEPRVLNAWAHWFVRREATLVAIADIRKGVKSRAKR
AKAGEEAAEPMLEGIDG