Protein Info for Rru_A2516 in Rhodospirillum rubrum S1H

Annotation: Multi-sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 805 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 306 to 327 (22 residues), see Phobius details PF08447: PAS_3" amino acids 415 to 498 (84 residues), 25.7 bits, see alignment E=1.2e-09 PF02518: HATPase_c" amino acids 673 to 782 (110 residues), 82.8 bits, see alignment E=2.4e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2516)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRC9 at UniProt or InterPro

Protein Sequence (805 amino acids)

>Rru_A2516 Multi-sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MAGLRFGVRSRLVLAFSAMAAMTLVTSAVAILSFSEVEARFIELTTTRLPAMAAATKLSQ
QAESIVAQAPALVAASSPTELHTIDFRIRDQLSWLAELIERVRKTDGEAIAMARVDDLAR
ELERRFVDLATQVERRLSMEALDRQTLGRLLVLGRTITGIRDQRETEGPPEDAAIARRWA
AGAQDANTVLIAALATTDAAILRNLGEAFGDLLETAETESARLSDPLSQDMRRSTAELRH
LGLGEAGIFNRRQAHMDITRGIQGTLTRNRLSGDLLSGASSQLADRIAEEAVKSALVLRA
ELHNRGAMMIVLSLFGVFGAGIVLLHLQRTVLRRLATLRAAMTAPLSTRPLVLEGSDDAD
EIGDMARALKGYAQAIADREHALRQSEGRFRAMATNVPGVLFQWFWRPLGEPRFLYVSPR
CQDLFGVSPALVLADWRKLGFSLEDQRAWVVRAAQAARDSRDWIQEGRIALANGGERWWR
VVAAPTPGEEPDTIILNGVLIDITALKDNERDLRAARQQAEQALSDLRSTQDTLVQAEKL
ASLGQLVAGIAHEINTPLGTGITGATFLDQETRQIAGRFRSGTLRRSELADYMERAEETA
RLIFTNLSRAGDLVQSFKQVAVDQVSDDRRTFALDTYIDEIFQSLNPRLRQTRLTVERAI
EPGLMVDGYPGVLFRILSNLVMNTLMHGFEPHETGTIRVEARLLPDSAPGRVELVYFDTG
KGIPHEIQGRVFDPFFTTRRGQGGTGLGLNIVYNLVTQSLGGTMTLSSHPGTGTTFTVVF
PIKAPRGVQAVPSPQPIKDSGAATA