Protein Info for Rru_A2476 in Rhodospirillum rubrum S1H

Annotation: Binding-protein-dependent transport systems inner membrane component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 80 to 102 (23 residues), see Phobius details amino acids 109 to 127 (19 residues), see Phobius details amino acids 133 to 155 (23 residues), see Phobius details amino acids 176 to 203 (28 residues), see Phobius details amino acids 254 to 275 (22 residues), see Phobius details amino acids 286 to 304 (19 residues), see Phobius details PF00528: BPD_transp_1" amino acids 147 to 307 (161 residues), 101.2 bits, see alignment E=3e-33

Best Hits

Swiss-Prot: 66% identical to PROW_SALTY: Glycine betaine/proline betaine transport system permease protein ProW (proW) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02001, glycine betaine/proline transport system permease protein (inferred from 100% identity to rru:Rru_A2476)

MetaCyc: 65% identical to glycine betaine ABC transporter membrane subunit ProW (Escherichia coli K-12 substr. MG1655)
RXN-8638 [EC: 7.6.2.9]; 7.4.2.- [EC: 7.6.2.9]

Predicted SEED Role

"L-proline glycine betaine ABC transport system permease protein ProW (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRG9 at UniProt or InterPro

Protein Sequence (357 amino acids)

>Rru_A2476 Binding-protein-dependent transport systems inner membrane component (NCBI) (Rhodospirillum rubrum S1H)
MADPASDPWGAAPPSPAETPAGDWLGGASAPPPAFDWADPFARPLIPLDDWTNQGLDWLV
LSFRPLFQAIRWPIDAVLTALNGTLVGVPPPVMLAIIALLAWQIAGRKMAIGSLISMTLI
GLIGAWSEAMLTLSLVLTSVMFCIALGLPSGILMARSDRLAKLSRPLLDAMQTTPAFVYL
VPIVMLFGIGNVPGVVVTIIFALPPLIRLTNLGIRQVPEDLVEAARSFGASKTQLLTKVQ
LPLALPTIMAGINQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVAIVLL
AILIDRLTQSMGVASAAQAKAPWYTSGPVGLVVRLVSLRKGTAHPARESLPKGEPIS