Protein Info for Rru_A2470 in Rhodospirillum rubrum S1H

Annotation: Ferrous iron transport protein B (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 786 transmembrane" amino acids 244 to 263 (20 residues), see Phobius details amino acids 284 to 309 (26 residues), see Phobius details amino acids 315 to 337 (23 residues), see Phobius details amino acids 347 to 368 (22 residues), see Phobius details amino acids 390 to 411 (22 residues), see Phobius details amino acids 424 to 449 (26 residues), see Phobius details amino acids 456 to 475 (20 residues), see Phobius details amino acids 513 to 534 (22 residues), see Phobius details amino acids 686 to 709 (24 residues), see Phobius details amino acids 716 to 738 (23 residues), see Phobius details amino acids 748 to 768 (21 residues), see Phobius details TIGR00231: small GTP-binding protein domain" amino acids 4 to 162 (159 residues), 42.5 bits, see alignment E=5.7e-15 PF02421: FeoB_N" amino acids 6 to 160 (155 residues), 215 bits, see alignment E=9.7e-68 PF01926: MMR_HSR1" amino acids 6 to 119 (114 residues), 73.8 bits, see alignment E=3.2e-24 TIGR00437: ferrous iron transport protein B" amino acids 10 to 711 (702 residues), 642.2 bits, see alignment E=9.2e-197 PF17910: FeoB_Cyto" amino acids 178 to 261 (84 residues), 52.6 bits, see alignment E=1.2e-17 PF07670: Gate" amino acids 354 to 447 (94 residues), 89.1 bits, see alignment E=6e-29 amino acids 515 to 714 (200 residues), 57.3 bits, see alignment E=4.9e-19 PF07664: FeoB_C" amino acids 457 to 509 (53 residues), 78.9 bits, see alignment 4.6e-26

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 100% identity to rru:Rru_A2470)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRH5 at UniProt or InterPro

Protein Sequence (786 amino acids)

>Rru_A2470 Ferrous iron transport protein B (NCBI) (Rhodospirillum rubrum S1H)
MSASVVCVVGNPNCGKTTLFNALTGGRQSVGNWPGVTVEKKVGAYRHGGEAVTIVDLPGV
YSLTPTSSSSEDERVARDYILSGEAGLVLNIVDASNLERNLYLTAQLLEMRVPMVVIVNM
MDIAASRHLDIDIDALSKSLDCKVVPMVASRRRGLDDLREVIAQSMGRTTPPAASAPYPP
AVSEAVGRIAATLPADSRADRRWTALQLLEGDSTLLRDLPPATALALESDLKQAAQSGTE
DFDILIADARYGFVGAIALGAVIRKGQMSRTLTDRIDKVVLHRVLGIPIFLAMMYLMFVF
TINVGGAFIDFFDQFAGTLFVDGFGHLLGGAGAPDWLTALLAKGVGGGVQTVATFIPVIG
FLYLFLSVLEDSGYMARAAFVMDRFMRGIGLPGKAFVPLIVGFGCNVPAVMATRTMDSRR
DRLITVMMAPFMSCGARLPVYVLFAAAFFPSGGQNLVFALYLIGILVAIATGLLLKTTAL
RGEASPFVMEMPPYHLPTVAGILLRTWDRLKSFILRAGKLVVAVVVVLSFLNSWGTDGSF
GNEDTDKSVLAAIGKAIVPVFAPMGISEENWPATVGVFTGIFAKEAVVGTLDALYGTIAE
GNAAAAQAEADPEAAATEEPEAFDLWGGLAGAFATIPANLSNVAGALADPLGIEVGDLSD
RSAVAADQEISTSSIDAIALLFDGAIGAFAYLLMVLLYMPCVAAVSAIWREVGTRWTLFA
AAWTTGMGYGAAVLTYQIGTFSRHPVSSAVDIAVVLAVLAAAIALLRLAGRGSAEAGPIS
AGQTAS