Protein Info for Rru_A2428 in Rhodospirillum rubrum S1H

Annotation: DSBA oxidoreductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 255 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF18312: ScsC_N" amino acids 39 to 72 (34 residues), 45.8 bits, see alignment 8.1e-16 PF13462: Thioredoxin_4" amino acids 95 to 249 (155 residues), 73.7 bits, see alignment E=4.3e-24 PF13098: Thioredoxin_2" amino acids 101 to 247 (147 residues), 27.1 bits, see alignment E=9e-10 PF01323: DSBA" amino acids 105 to 247 (143 residues), 76.7 bits, see alignment E=4.3e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2428)

Predicted SEED Role

"Protein-disulfide isomerase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRL7 at UniProt or InterPro

Protein Sequence (255 amino acids)

>Rru_A2428 DSBA oxidoreductase (NCBI) (Rhodospirillum rubrum S1H)
MTFALRPLRALRPLLLAATLIGGALAPALAAEDSLSPAQQAAVRALIRDTLVSDPEILRE
AVQALQAKDEAEASAQQARAIKDLGPLLHSPEGLPALGNPKGDVTVIEFSDYNCGYCKRV
FPVLWDEVEADGQIKLYVMEYPILGAESVMAARAALAAIGQDKYAEFHKALMAHKGKFTE
EAIAGIARAQGLDAAKLKTAMAGKEVDAALARSFQIGQALGISGTPAFIVADRLVPGALD
PATLKALVKEARSGK