Protein Info for Rru_A2400 in Rhodospirillum rubrum S1H
Annotation: Ribulose-bisphosphate carboxylase, form II (NCBI)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to RBL2_RHORT: Ribulose bisphosphate carboxylase (cbbM) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
KEGG orthology group: K01601, ribulose-bisphosphate carboxylase large chain [EC: 4.1.1.39] (inferred from 100% identity to rru:Rru_A2400)MetaCyc: 100% identical to ribulose bisphosphate carboxylase subunit (Rhodospirillum rubrum)
Ribulose-bisphosphate carboxylase. [EC: 4.1.1.39]
Predicted SEED Role
"Ribulose bisphosphate carboxylase (EC 4.1.1.39)" in subsystem AMP to 3-phosphoglycerate or CO2 uptake, carboxysome or Calvin-Benson cycle or Photorespiration (oxidative C2 cycle) (EC 4.1.1.39)
MetaCyc Pathways
- Rubisco shunt (10/10 steps found)
- Calvin-Benson-Bassham cycle (12/13 steps found)
- photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (20/26 steps found)
- ethene biosynthesis V (engineered) (19/25 steps found)
- oxygenic photosynthesis (13/17 steps found)
- 1-butanol autotrophic biosynthesis (engineered) (20/27 steps found)
- nucleoside and nucleotide degradation (archaea) (3/10 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 4.1.1.39
Use Curated BLAST to search for 4.1.1.39
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q2RRP5 at UniProt or InterPro
Protein Sequence (466 amino acids)
>Rru_A2400 Ribulose-bisphosphate carboxylase, form II (NCBI) (Rhodospirillum rubrum S1H) MDQSSRYVNLALKEEDLIAGGEHVLCAYIMKPKAGYGYVATAAHFAAESSTGTNVEVCTT DDFTRGVDALVYEVDEARELTKIAYPVALFDRNITDGKAMIASFLTLTMGNNQGMGDVEY AKMHDFYVPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKPKLGLRPKPFAEAC HAFWLGGDFIKNDEPQGNQPFAPLRDTIALVADAMRRAQDETGEAKLFSANITADDPFEI IARGEYVLETFGENASHVALLVDGYVAGAAAITTARRRFPDNFLHYHRAGHGAVTSPQSK RGYTAFVHCKMARLQGASGIHTGTMGFGKMEGESSDRAIAYMLTQDEAQGPFYRQSWGGM KACTPIISGGMNALRMPGFFENLGNANVILTAGGGAFGHIDGPVAGARSLRQAWQAWRDG VPVLDYAREHKELARAFESFPGDADQIYPGWRKALGVEDTRSALPA