Protein Info for Rru_A2398 in Rhodospirillum rubrum S1H

Annotation: Pyruvate-ferredoxin (flavodoxin) oxidoreductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1186 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 1 to 1173 (1173 residues), 1679.9 bits, see alignment E=0 PF01855: POR_N" amino acids 13 to 243 (231 residues), 283.7 bits, see alignment E=7.8e-88 PF17147: PFOR_II" amino acids 265 to 347 (83 residues), 42.6 bits, see alignment 4.1e-14 PF01558: POR" amino acids 429 to 611 (183 residues), 106.2 bits, see alignment E=1.3e-33 PF10371: EKR" amino acids 628 to 680 (53 residues), 83 bits, see alignment (E = 6.1e-27) PF00037: Fer4" amino acids 686 to 706 (21 residues), 28.7 bits, see alignment (E = 5e-10) amino acids 744 to 759 (16 residues), 22.7 bits, see alignment (E = 3.9e-08) PF12837: Fer4_6" amino acids 686 to 706 (21 residues), 30.3 bits, see alignment (E = 1.8e-10) PF13484: Fer4_16" amino acids 691 to 759 (69 residues), 33.4 bits, see alignment 4e-11 PF12838: Fer4_7" amino acids 691 to 759 (69 residues), 39.9 bits, see alignment 2.9e-13 PF13187: Fer4_9" amino acids 691 to 760 (70 residues), 31.4 bits, see alignment 9.5e-11 PF02775: TPP_enzyme_C" amino acids 963 to 1075 (113 residues), 39.6 bits, see alignment E=2.8e-13

Best Hits

Swiss-Prot: 100% identical to NIFJ_RHORT: Pyruvate-flavodoxin oxidoreductase (nifJ) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q53046 at UniProt or InterPro

Protein Sequence (1186 amino acids)

>Rru_A2398 Pyruvate-ferredoxin (flavodoxin) oxidoreductase (NCBI) (Rhodospirillum rubrum S1H)
MVAIDGNEACASVAYRVSEVAVIYPITPSSTMGELSDEWSAKGLTNIWGAVPQVVEMQSE
GGAAGACHGAIQTGSLGTTFTASQGLLLMIPNMYKIAGELTPFCMHVTARTLATHALSIF
GDQSDVMACRQTGFAILASASVQEAHDLASVAHGASLESRIPFLHFFDGFRTSHEVNKIE
LMTDDDLHAMIDDDLVAAHRARALTPDTPVTRGTAQNPDTFFQAQEARNPFYDACPAIVQ
SYMDRLAALTGRRYGLFDYVGHPQAERVVVIMGSGAETVAETVDWLVARGEKIGVVKVRL
FRPFSVDAFVAALPVSVRAIAVLDRCKESGAIGEPLYLDVVGALARAKALGLRAGIVDPA
VIGGRYGLSSKEFTPAMVKAIFDELAKANPKQAFTVGIEDDVTHLSLSVDRSFRIESADI
KRSVFFGLGADGTVGANKNSIKIISDSPTIHGQGYFVYDSKKSGAITISHLRFGPRPIRA
PYLIDEADFIACHHFSFLDKVDVLETAAVGATLLLNSPHDKDTVWDALPRPVQQTIIDRD
LKLFVIDANKVAQETGMGQRINTIMQTCFFALSGVMPRDEAIEEIKKAISKTYARKSQKV
IDANFAAVDQTLSRLQSVTIPGVLTGHALPPLVSAGAPDFVRNVTAVMLAGKGDSLPVSA
MPVDGTWPTETARWEKRDIAQQVCSWDADLCIQCNKCVMVCPHAALRVKAVPAEAAAALP
ASMNSTPYKGKDDLKGSAYVLALSPEDCTGCGICVEACPGKDKATGARSLTMHAREDVVS
ACKENWEIFLDLPDVARTSLRPTVKNSQFMTPLFEFSGACQGCGETPYLKLLTQMWGDRL
MIANATGCSSIYGGNLPTSPYAKDANGRGPAWSNSLFEDNAEFGLGFRLALDQHRSEAKR
LLGALAPQLSGVLVDGLVANAANNDEAAIAAQRERVVSLRAELGGLTGWQARALEGLADY
LVEKVVWIVGGDGWAYDIGYGGLDHVISSGRNVNILVMDTEVYSNTGGQQSKSTPIGASA
KFSVAGKALPKKDLGQIAMANGHVYVASIAFGASDNQTLRALSEAVSYEGPSLIIAYSHC
IAHGYDLTCGLSQQKLAIETGYWPLYRFDPRKMGVGPALSLDGVQPSRPIGDYMANEGRF
RIIRDADPERYAMLLEAAEENVRSRWALLRQLAGVADEQEGARAAQ