Protein Info for Rru_A2330 in Rhodospirillum rubrum S1H

Annotation: Response regulator receiver domain protein (CheY) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 124 PF00072: Response_reg" amino acids 5 to 117 (113 residues), 89.8 bits, see alignment E=6.9e-30

Best Hits

Swiss-Prot: 34% identical to CHEY_HELPY: Chemotaxis protein CheY homolog (cheY) from Helicobacter pylori (strain ATCC 700392 / 26695)

KEGG orthology group: K03413, two-component system, chemotaxis family, response regulator CheY (inferred from 100% identity to rru:Rru_A2330)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRW5 at UniProt or InterPro

Protein Sequence (124 amino acids)

>Rru_A2330 Response regulator receiver domain protein (CheY) (NCBI) (Rhodospirillum rubrum S1H)
MTSTIFLVDDSATVLMSMETILRRAGFTIAQASSGEDALAQLEKGLKPALIITDIHMPGM
NGIDLIRKVRTMAGFQFIPILVVTTESQQSKRDEARAAKATGWLVKPVQPDDLLKVVKQI
LPNG