Protein Info for Rru_A2317 in Rhodospirillum rubrum S1H

Annotation: Pyruvate carboxylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1146 PF00289: Biotin_carb_N" amino acids 5 to 114 (110 residues), 137 bits, see alignment E=1.5e-43 TIGR01235: pyruvate carboxylase" amino acids 8 to 1145 (1138 residues), 1753.6 bits, see alignment E=0 PF02786: CPSase_L_D2" amino acids 120 to 326 (207 residues), 231.3 bits, see alignment E=3.8e-72 PF07478: Dala_Dala_lig_C" amino acids 148 to 296 (149 residues), 27.3 bits, see alignment E=9.8e-10 PF02785: Biotin_carb_C" amino acids 348 to 456 (109 residues), 113.5 bits, see alignment E=2.1e-36 PF00682: HMGL-like" amino acids 535 to 806 (272 residues), 96.1 bits, see alignment E=1.1e-30 PF02436: PYC_OADA" amino acids 830 to 1029 (200 residues), 248 bits, see alignment E=3e-77 PF00364: Biotin_lipoyl" amino acids 1079 to 1144 (66 residues), 55.3 bits, see alignment 1.9e-18

Best Hits

KEGG orthology group: K01958, pyruvate carboxylase [EC: 6.4.1.1] (inferred from 70% identity to amv:ACMV_29950)

Predicted SEED Role

No annotation

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.4.1.1

Use Curated BLAST to search for 6.4.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRX8 at UniProt or InterPro

Protein Sequence (1146 amino acids)

>Rru_A2317 Pyruvate carboxylase (NCBI) (Rhodospirillum rubrum S1H)
MGQKIKRLMVANRSEIAIRVFRAAAELGIRTVALYAEEDRLSLHRFKADEAYRVGAGKGP
LQAYLAIDDIIDIATREKIDAIHPGYGFLSEDPAFAEACAAAGIRFIGPTPETLRQLGNK
VAARNLARSLGVPVMPATGPLPTDPGVIHRLAKDIGYPVMLKASWGGGGRGMRPIDSEEH
LLDAVTTSRREAAAAFGKDEVYLEKLVRAARHVEVQLLGDSHGTLVHLFERDCSIQRRHQ
KVIERAPAPYLDSETRRRLTDAALKIGRATGYVGAGTVEFLMDVATNDFFFIEVNPRIQV
EHTVTEVVTGLDLVKAQIRIAEGGHIGQTAETGIPAQEAICLNGHAMQCRITTEDPERGF
VPDYGRISAYRGASGFGIRVDGGTAYSGAVVTPFYDAMLEKVTAWAPTPDEVIARMERVL
REYRIRGIATNLPFLEAILAHPDFRATRYTTRFIDETPALFNSPRRRDRATKLLTYIADI
TVNGHPEMAGRPPRAVARIPEPPRLGTTRREGTKQGLDRLGADGFARWMRAQDRVLITDT
TLRDAHQSLLATRLRSYDIVRAAEAYATGLPDLLSLECWGGATFDVALRFLSEDPWERLA
AIRERVPNILLQMLLRGANGVGYTNYPDNVVRFFVARAAEGGIDLFRIFDCLNWIDNMRV
AIDAVCEAGKIAEGAICYTGDILDPDRAKYSLRYYVDLAQQLDAAGCHVIAIKDMAGLLS
PKAAKVLVRVLRNVTDRPLHLHTHDTSGTAAATLIAAIDAGVDAVDLAMDALSGTTSQPC
LGSVVAAIGKSDRDSGLDAEAIRRMSLYWEDVRALYGAFESDLRAGASEVYLHEMPGGQF
TNLKEQARALGLANRWHDVAAAYRQANDLFGDIVKVTPSSKVVGDMALMMVSQGLTPEDV
LNPDRDIAFPASVVDMLKGDLGQPYGGWPEALRKKVLKGQAPLTVRPGALLGTADLGALR
AKTAAEIGRPVDNRDLASALMYPKVFADFARATETWGPVAVLPTPTFFGGMKVGEEIVVE
IEPGKSLIIVLQAIGAAEPDGKVKLFFELNGQPRVIRVADRSRVAAPPRPKAIEGDDRQV
AAPMAGAVSSILAHKGQAVAAGDPLLTLEAMKMETTLHAPRDGIVADLLVQVQETVESKD
LLLLLQ