Protein Info for Rru_A2232 in Rhodospirillum rubrum S1H

Annotation: Two Component Transcriptional Regulator, LuxR family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 PF00072: Response_reg" amino acids 3 to 115 (113 residues), 66.9 bits, see alignment E=2.6e-22 PF00196: GerE" amino acids 151 to 205 (55 residues), 60.6 bits, see alignment E=1.3e-20 PF08281: Sigma70_r4_2" amino acids 152 to 194 (43 residues), 26.1 bits, see alignment 8e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2232)

Predicted SEED Role

"COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RS63 at UniProt or InterPro

Protein Sequence (212 amino acids)

>Rru_A2232 Two Component Transcriptional Regulator, LuxR family (NCBI) (Rhodospirillum rubrum S1H)
MRVMIVDDHELFRNGLRFQLAAIDSTLDVVEADTFEDCIRLATEDGPVSKVFLDLMMPDM
DWREALSALRRLPDPPDVVVLSGADDVAMIRSAIDHGACGYIPKSLKGDVLESALRLILA
GGFYITPEVYRGPRVYDGAVRIMGVGGDDVPLTPRQKEVLAHIDAGLSNRQIAQAMTLSE
ATVKMHIGRLFKALGAQSRTDALAVARRKGML