Protein Info for Rru_A2154 in Rhodospirillum rubrum S1H

Annotation: Biopolymer transport protein ExbD/TolR (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 transmembrane" amino acids 26 to 47 (22 residues), see Phobius details TIGR02801: protein TolR" amino acids 18 to 138 (121 residues), 127.4 bits, see alignment E=2.6e-41 PF02472: ExbD" amino acids 18 to 137 (120 residues), 108.2 bits, see alignment E=1.6e-35

Best Hits

Swiss-Prot: 39% identical to EXBD_SHIFL: Biopolymer transport protein ExbD (exbD) from Shigella flexneri

KEGG orthology group: K03559, biopolymer transport protein ExbD (inferred from 100% identity to rru:Rru_A2154)

MetaCyc: 39% identical to Ton complex subunit ExbD (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Biopolymer transport protein ExbD/TolR" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSE1 at UniProt or InterPro

Protein Sequence (155 amino acids)

>Rru_A2154 Biopolymer transport protein ExbD/TolR (NCBI) (Rhodospirillum rubrum S1H)
MAGALLPSGDDEGGYKPIAEINITPMVDVMLVLLIIFMVAAPLMSMGVPVDLPRTQAAEA
QPPKDPVVVSIDQTGALFLRDQPLAEADMDARLAALAKEKPGSVVYVRGHKDLPYGRVME
VMGRIGQAGFAKVSLMAEMPTPPAAAGAAATGTGR