Protein Info for Rru_A2141 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF6, transmembrane (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 320 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 45 to 67 (23 residues), see Phobius details amino acids 79 to 99 (21 residues), see Phobius details amino acids 111 to 132 (22 residues), see Phobius details amino acids 139 to 158 (20 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 224 to 250 (27 residues), see Phobius details amino acids 258 to 280 (23 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details PF00892: EamA" amino acids 12 to 155 (144 residues), 42.9 bits, see alignment E=2.8e-15 amino acids 167 to 300 (134 residues), 59.3 bits, see alignment E=2.3e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2141)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSF4 at UniProt or InterPro

Protein Sequence (320 amino acids)

>Rru_A2141 Protein of unknown function DUF6, transmembrane (NCBI) (Rhodospirillum rubrum S1H)
MPHSRPLSRLRASLILLLVSFIWGSAFVAQKTAFDAVEGATAPALGPLAFTGARFLLGAL
VVLPFALRENRQARSRGAPGAGLLAIFCGIGAVLFAASFTQQLGIIGTSVTNAGFLTALY
VPLVPVVALVIFRQSVRKMIWPGAAGCLAGLWLLTGAATNGLSALTAGDLWVLVGALFWA
FHVTVVGVMATRSGRPLTLAAAQFLTCGVLGWAGAFAFETPTLAGMAAIAPEIAYAGILS
VGVAFTLQVVAQRHTHPAAAAIILSMEMVFASLAAVVVLGERLSGVQWLGAGLILASIIA
VESAAALGDRRRGAAGALTP